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Biomedical subjects

V Köpruner

Publications and source records attributed to V Köpruner.

5 recordsLinked to original sources
PubMed1985

Quantitative EEG study in patients with cerebral ischemia during nimodipine treatment.

In a group of 15 patients with chronic unilateral cerebral ischemia, a quantitative EEG study was performed before, during and after nimodipine (Bay e 9736) infusion (1 microgram/kg/min). The EEG was recorded bipolarly from the rolandic region. After computerized EEG analysis, a multiparametric asymmetry score (MAS) was calculated; this MAS provides a sensitive indicator for discrimination between neurologically normal subjects and patients with unilateral ischemia. A positive MAS is characteristic for healthy subjects, a negative one for ischemia patients. During nimodipine treatment, the MAS became more negative (increased EEG asymmetry) in 7 and less negative (decreased EEG asymmetry) in 8 patients. A correlation was found between the direction of the EEG asymmetry changes and the localization of the infarcted area as seen in the CT scan.

Adult↗
PubMed1984

Multiparametric asymmetry score (MAS)--distinction between normal and ischaemic brains.

A multiparametric asymmetry score (MAS) is presented. It is based on the EEG data of 50 normal subjects and 32 patients with cerebral ischaemia. For the asymmetry measurements, the following parameters appeared to be the most powerful in the given order: the ratio theta/beta power, the peak frequency, absolute delta and theta powers and the ERD in the alpha band. The EEG data were recorded during rest and during voluntary hand movements from the centro-temporal regions. As the MAS can be calculated with or without the peak frequency parameter, it is applicable to all types of EEG data. Using the MAS, 94% of the normal and 92% of the patient data were correctly classified. From the patient group, 6 were without neurological deficits and 9 had 'normal' clinical EEGs.

Discrimination, Psychological↗