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Biomedical subjects

V Kalidasan

Publications and source records attributed to V Kalidasan.

5 recordsLinked to original sources

Congenital segmental dilatation of the duodenum--differential diagnosis for an antenatally-diagnosed intra-abdominal cyst.

We report the third case of segmental dilatation of the duodenum and the first to be diagnosed antenatally. The lesion presented as an intra-abdominal cyst on an antenatal scan at 17 weeks and was followed up with more specific investigations after birth. The final diagnosis was obtained only at laparotomy where the dilated segment was resected. The patient is well at eighteen month follow-up. Segmental dilatation of the gastrointestinal tract, although rare, should be considered in the differential diagnosis of antenatally discovered intra-abdominal cysts.

Cysts↗

Rare pancreatic tumours in children (other than nesidioblastosis).

BACKGROUND: The rarity of pancreatic tumours other than nesidioblastosis in children is such that the experience of any one surgeon or institution is small. As a consequence, there is limited information on the appropriate management and outcome of these tumours. For this reason a review was conducted of the experience of a large paediatric surgical institution. METHODS: During a 23-year period, six patients with pancreatic tumours other than nesidioblastosis were treated at the Royal Children's Hospital, Melbourne. RESULTS: Despite the varied modes of presentation and surgery undertaken, all six patients with surgery alone, with follow-up from 1 to 18 years. Two of the tumours were malignant; the remaining four being islet cell adenomata. No form of adjuvant treatment (chemotherapy or radiotherapy) was used. CONCLUSION: These rare paediatric tumours appear to have a good prognosis, even when malignant, and respond well to radical surgical ablation. Adjuvant therapy appears to be unnecessary.

Adenoma, Islet Cell↗

The Dandy-Walker syndrome--a 10-year experience of its management and outcome.

Hydroephalus of childhood may be associated with intracranial haemorrhage, infection, aqueductal stenosis, Arnold-Chiari malformation (spina bifida), tumours or more uncommonly with the Dandy-Walker syndrome (DWS). We present our experience with the management of this condition over a 10-year period. Twelve children with a definite diagnosis of DWS are reviewed with regard to the age at diagnosis, investigations, treatment, associated problems and overall outcome. Two patients died; there was a high incidence of mental retardation (65%) and associated problems. All but one child had ventriculo-peritoneal shunting and two had cysto-peritoneal shunts in addition to their V-P shunts. There were no familial cases; one child had a chromosomal abnormality. Although the long-term outcome is dismal in most cases, about 35% of the children have a reasonable outcome and hence the condition warrants energetic treatment.

Child↗