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Biomedical subjects

V Kolín

Publications and source records attributed to V Kolín.

4 recordsLinked to original sources
PubMed1985

[Small and large intestine devascularization (devitalization) and potentials in the therapeutic use of this operative method].

The experimental findings with devitalization of various intestinal segments by means of devascularization showed that the isolated segments left in peritoneal cavity (together with their contents) were gradually destroyed and changed into a slight fibrous residue. The retaining of the up to 180 cm long segment did not endanger the life of experimental animals. This experience was used in the surgical treatment of inoperable tumours in left half of large intestine and in rectosigmoideum. The case report of four successful operations is given together with two cases of invagination of the devitalized part into intestinal lumen.

Adenocarcinoma, Scirrhous↗
PubMed1985

Experimental elimination of various intestinal segments by means of devascularization (devitalization).

Segments of the small and large intestine, of varying lengths (10-180 cm), were devascularized by simultaneously ligating the mesenteric arteries and veins. When the circulation had been cut off, the ends of the devascularized segment were both ligated, continuity of intestinal passage was renewed by forming an anastomosis and the isolated segment was left in situ, together with its contents. Contrary to accepted views, no changes leading to death (necrosis and peritonitis) occurred, but the devascularized tissue was progressively destroyed and reconstructed until, after four weeks, all that was left was a minute fibrous residue. None of 41 pigs died as a result of devascularization, including those in which large doses of pathogenic microorganisms were injected into the isolated segment. The possibility of employing this technique in the surgical treatment of inoperable tumours is discussed.

Animals↗