Biomedical subjects

V Krupar

Publications and source records attributed to V Krupar.

At least 19 recordsLinked to original sources

PubMed1989

[Immunologic examination of the synovial fluid in the differential diagnosis of knee joint inflammations. Computer analysis of 275 patients].

In the synovial fluid of the knee joint 15 immunological indicators were assessed in 275 patients divided into three groups according to the following diagnoses: rheumatoid arthritis, gonarthritis and synovitis after a blunt injury. The assembled data were evaluated by a stepwise discrimination analysis. This made it possible to select eventually in the compared groups eight characteristics with a differentiating value: IgE, immunocomplexes, beta-2 microglobulin, C3, CRP, alpha-2 macroglobulin, LF-test--reciprocal titre, LF-test--square of reciprocal titre. The classification functions of these characteristics make the correct classification of a random patient with a probability of 78.8-92% possible.

Adult↗

PubMed1989

[Clinical importance of changes in antibody immunity in gout].

In 77 patients with gout (16 with acute attacks and 61 during an attack-free period), in 30 healthy subjects, 30 patients with IgM RF serum positive rheumatoid arthritis (RA) and 20 cases of IgM RF serum negative RA the authors examined serum values of 10 parameters of antibody immunity: IgA, IgG, IgM, IgD, IgE, beta-2 microglobulin (beta-2 MG), immunocomplexes (IK), IgM RF/LFT, IgM/RF/HAT and ANA/IF. Data obtained by quantitative analyses were processed by stepwise discrimination with the consecutive selection of characteristics significant for the differentiation of the investigated groups and by assessment of classification functions which make it possible to classify individuals selected at random. The authors consider the following particularly important from the clinical aspect: acute gouty attack--IgM RF serum positive RA (IK and beta-2 MG), attack-free stage of gout--healthy subjects (IgA, IgG, IgM, IgD, IK, IgE). IgM RF were detected in 5/77 patients with gout, ANA/IF not in a single patient.

Acute Disease↗

PubMed1989

[Methodological approach to the study of effectiveness of health services. II].

The paper deals with theoretical problems associated with the evaluation of medical, social and economic effectiveness, and the authors mention different approaches to the evaluation of provision concerning the health of some population groups and provisions concerning the population as a whole. Attention is also focused on information problems of effectiveness. In the paper formulae and methodological aspects are given which can be used for the calculation of the economic effect of various prosions which reduce the morbidity, which help to save human lives or lead to an increased productivity of labour. In the conclusion methodological recommendations are given for the approach in investigations of the effectiveness of health care.

Evaluation Studies as Topic↗

PubMed1987