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V L Gupta

Publications and source records attributed to V L Gupta.

14 recordsLinked to original sources

Electron acceleration by a self-diverging intense laser pulse.

Electron acceleration by a laser pulse having a Gaussian radial and temporal profile of intensity has been studied. The interaction region is vacuum followed by a gas. The starting point of the gas region has been chosen around the point at which the peak of the pulse interacts with the electron. The tunnel ionization of the gas causes a defocusing of the laser pulse and the electron experiences the action of a ponderomotive deceleration at the trailing part of the pulse with a lower intensity rather than an acceleration at the rising part of the laser pulse with a high intensity, and thus gains net energy. The initial density of the neutral gas atoms should be high enough to properly defocus the pulse; otherwise the electron experiences some deceleration during the trailing part of the pulse and the net energy gain is reduced. The rate of tunnel ionization increases with the increase in the laser intensity and the initial density of neutral gas atoms, and with the decreases in the laser spot size, which causes more defocusing of the laser pulse. The required initial density of neutral gas atoms decreases with the increase in the laser intensity and also with the decrease in the laser spot size.

Journal Article↗

Gangrene and renal failure caused by dihydroergotamine used to treat raised intracranial pressure following head trauma.

A case of peripheral gangrene and renal failure following the use of dihydroergotamine (DHE) for treatment of raised intracranial pressure (ICP) is reported. There have been several reports of vasospasm and peripheral gangrene caused by DHE used in combination with heparin for prevention of deep venous thrombosis. Clinical experience with the use of DHE in head trauma is limited. This case report emphasises the seriousness of the adverse effects associated with the use of this drug.

Aged↗

Efficacy of zinc therapy in prevention of crisis in sickle cell anemia: a double blind, randomized controlled clinical trial.

145 patients were recruited in the trial while 130 completed it. Patients were randomized to receive zinc sulphate capsules. 220 mgm three times a day or identical placebo. Major outcome variable was 'Sickle cell crisis'. After a follow up of 1.5 years, the mean number of episodes of crisis was 2.46 +/- 1.04 in the intervention group and 5.29 +/- 2.58 in the control group (p < 0.025; 95% CI for difference between groups: 1.98, 3.42). Mean duration of hospital stay was 4.3 +/- 2.2 days in the intervention group and 3.9 +/- 1.6 days in the control group. The difference was not significant (p > 0.05). There was a significant reduction of the mean number of infective episodes and associated morbidity in patients with sickle cell anaemia.

Administration, Oral↗