PubMed Health⌕ Search

Biomedical subjects

V L Landry

Publications and source records attributed to V L Landry.

7 recordsLinked to original sources

Should Level I trauma centers be rated NC-17?

BACKGROUND: Previous studies have reached contradictory conclusions regarding where injured children are best treated. Our hypothesis was that no differences in survival outcome exist among trauma centers caring for pediatric patients. METHODS: For 16,108 injured children, we created a dependant variable, As-Ps (actual survival--predicted survival), which represents variation from TRISS-predicted outcome for each individual. We then used that variable to compare trauma centers' survival results overall and results for liver, spleen, and head injuries, statistically adjusting for age and injury severity. RESULTS: When adjusted for age and injury severity, centers with added qualifications in pediatrics and Level I centers had improved survival performance overall and in the subcategory of head injured children. No differences existed in other organ-specific injury categories. CONCLUSION: The improved unexpected outcome results at Level I centers and centers with Added Qualifications in Pediatrics suggest that a team of qualified professionals working in an institution willing to commit the required resources can sufficiently offer injured children the survival advantage expected of a trauma center.

Child↗

Comparison of measures of physiologic stress during treadmill exercise in a patient with 20% lower extremity burn injuries and healthy matched and nonmatched individuals.

Patients with burn injuries are referred for rehabilitation within days after the injuries to encourage early ambulation and functional training. Many of these patients are hypermetabolic at rest. Metabolic demands of activity are added to the already hypermetabolic state and elevate total energy requirements and some physiologic measures. Reports on the physiologic stress imposed by therapeutic activities for patients with burn injuries are limited to low levels of metabolic demand (< or =2 metabolic equivalents [METS]). The degree of stress imposed by functional activities such as ambulation (3 METS) and stair climbing (5 METS) is not known for adults with burn injuries. The purpose of this study was to report the clinical measures of myocardial and physiologic stress in a patient with 20% lower extremity total body surface area burns during an exercise challenge equivalent to stair climbing. Physiologic measures were assessed before and during a treadmill activity (5 METS) for a 40-year-old obese man 3 weeks after he had lower extremity burn injuries. These measures were compared with mean values for 62 healthy counterparts and 6 healthy subjects matched for age, gender, and fitness level. Heart rate, systolic blood pressure, rate pressure product, and the rating of perceived exertion for the patient with burn injuries were higher at baseline and during exercise than the mean values for the 62 healthy individuals and the 6 matched subjects. The steady state exercise values for heart rate, systolic blood pressure, rate pressure product, and rating of perceived exertion at 6 minutes were 189 beats per minute, 190 mm Hg, 3591, and 17, respectively, for the patient with burn injuries and were 111.3 beats per minute, 149 mm Hg, 1680, and 11.7, respectively, for the 6 matched subjects. Ventilation during exercise also increased for the patient with burn injuries more than for the matched subjects (3/4 vs 1/4). Pain experienced by the patient with burn injuries decreased with activity (9.8 vs 7.3 on a 15-cm scale). Treadmill walking produced near maximal responses for most physiologic measures for this patient who was hypermetabolic at rest. We provided normative data to assist therapists who work with patients with similar burn injuries.

Adult↗

The publication outcome for the papers presented at the 1990 ABA conference.

This retrospective review of the 1990 ABA orally presented abstracts found an overall publication rate of slightly more than 26%. This included both same-content and related-content publications. When the abstracts were made a subset by theme, a major variance in the publication rates was found. Abstracts that had a psychologic content (72.73%), for example, fared much better than reports of in vitro research (6.9%). This overall rate when compared to publication studies in other clinical areas was found to be quite low. This study further found that there was a great deal of similarity between abstracts that were published and those that were not. The one meaningful predictor of ultimate journal publication was the clarity of the presentation of statistically related information.

Burns↗

Animal extremists: a cause for concern?

Investigators in various biomedical specialties, as well as hunters, farmers, and fur ranchers, have been victimized by animal rights extremists in the United States, the United Kingdom, and other countries during recent years. Given the extent of animal-based burn research, in which rodents and higher mammals are subjected to burn and smoke trauma, the potential for a liberation attack by an animal rights fringe group must be taken seriously. Suggestions are given to researchers and their institutions to prevent or minimize such an attack.

Animal Rights↗

An introduction to the biostatistical technique of resampling.

This article will introduce resampling method to burn injury researchers and care givers. With the use of a data set taken from a published burn injury research project, this technique is extensively described and fully illustrated in a stepwise fashion by tables and figures. The recent exponential growth in the use of this method has produced a concurrent need to understand its fundamentals. Researchers, reviewers, and care givers will need to be familiar with resampling to evaluate the published results of various studies. Additionally, as burn research continues to focus on the molecular and cellular aspects of injury and healing, data analysis by resampling might prove to be a useful adjunct to standard biostatistical methods. Many useful links on the Internet (starting at www.statistics.com) can be followed for further readings, software, and tutorials.

Burns↗