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V Lal

Publications and source records attributed to V Lal.

26 records · Page 2Linked to original sources
PubMed1997

Comparison of cellular responses in single- and multiple-lesion neurocysticercosis.

Leucocytes from 14 cases of neurocysticercosis who had multiple lesions showed a significantly lower level of chemotaxis than those from healthy controls [with mean (S.D.) movements of 49.86 (15.0) and 89.1 (12.9) microns, respectively; P < 0.05). In contrast, the leucocytes from 14 cases with single lesions had similar chemotactic responses to the controls. Although the level of lymphoproliferation stimulated with phytohaemagglutinin, a measure of T-lymphocyte function, was also considerably less using cells from the multiple-lesion cases than when cells from the single-lesion cases were used, the difference was not statistically significant [0.644 (0.248) of control values v. 0.463 (0.317); P < 0.1]. Flow cytometry indicated that the total numbers of CD4 cells and CD4/CD8 ratios in all blood samples were normal. It therefore appears that, among neurocysticercosis patients, only those with multiple lesions have defective neutrophils and may also have dysfunctional lymphocytes.

Adolescent↗
PubMed1997

Cerebellar degeneration following neuroleptic malignant syndrome.

A 55-year-old woman with a history of bipolar affective disorder developed hyperpyrexia, rigidity and depressed consciousness (neuroleptic malignant syndrome) after commencing neuroleptic therapy. On regaining consciousness, she was mute and had signs suggesting pancerebellar involvement. Hyperpyrexia, which is a cardinal feature of neuroleptic malignant syndrome, may have caused cerebellar damage. Neuroleptic malignant syndrome needs both early recognition and prompt treatment to obviate devastating complications.

Cerebellar Diseases↗
PubMed1994

Non-invasive detection of Chlamydia trachomatis genital infections in asymptomatic males and females by enzyme immunoassay (Chlamydiazyme).

First voided urine, urethral and cervical swabs were collected from 300 asymptomatic inmates made up of 200 males and 100 females from prisons in Fiji. The enzyme immunoassay for detection of chlamydial antigen test was performed on the sediment of the urine samples. The prevalence of chlamydial urethritis in the study population of men as determined by culture of urethral swabs was 15%. Compared with the urethral cultures for chlamydia the urine EIA had a sensitivity of 86.6% and a specificity of 98.2%. In women the incidence of urogenital chlamydia infection was 18%. Using the results of the cervical swabs as a reference standard the urine EIA in the females showed a sensitivity of 61.1% with a specificity of 97.6%. Culturing urine sediments from both men and women showed low results (30.0% for men and 22.2% for women). The rapid enzyme immunoassay testing of male FVU sediment appears to be a reliable, non-traumatic and rapid method of diagnosing Chlamydia infection. The judicious use of this non-invasive method may help in detecting and treating men, thus reducing the rapid spread of the pathogen in the community.

Adult↗