[A case of cell-mediated acquired immunodeficiency appearing with a picture of fever of unknown origin].
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Biomedical subjects
Publications and source records attributed to V Lampronti.
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A case of endocarditis in 17 year old female with a psychomotor and neurovegetative disorder is presented. Serum and cultural data as well as the excellent response to treatment with 5-flucytosine seems to confirm the diagnosis of candida infection.
The authors investigate the alexithymia phenomenon and the possibility of quantifying it by administering the Schalling-Sifneos Personality Scale on four groups of subjects: asthmatics, psychosomatics other than bronchial asthmatics, patients afflicted with non-psychosomatic chronic illnesses and healthy subjects. The questionnaire permits a quantitative evaluation of the alexithymia phenomenon that appears significantly more evident in asthmatics than in patients afflicted with chronic illnesses and healthy subjects. The patients afflicted with psychosomatic illnesses other than asthma attain higher scores than asthmatic patients. The authors identify certain items on the scale as being particularly associated with the alexithymia phenomenon, enough to be able to construct a partial alexithymia score, indicative in itself of the presence of alexithymia personality traits, even in the absence of particularly high total alexithymia scores. Variations in age and educational level influence scores obtained by healthy subjects and patients afflicted with chronic illnesses, while this does not occur in asthmatics and other psychosomatic patients. This seems to indicate that the higher scores of the latter are not influenced by social or statistical types of factors, but rather by illness-related factors.
We report the case of a rather rare form of K-light chain deposition disease (LCDD) in a 61-year-old man with hypertension and rapidly progressing nephropathy. Laboratory findings prompted suspicion of the diagnosis which was confirmed by light-microscopic and immunofluorescent studies of samples taken by percutaneous renal and liver biopsy. Hepatic and urinary K-light chains were present; no circulating light chains were detected. Bone marrow examination evidenced mild infiltration of lymphoid cells, all positive for K-light chain staining. Plasma cells were within normal ranges. LCDD appeared as nodular glomerulosclerosis with rare crescents and extensive tubular involvement with K-light chain deposits. There was no evidence of altered liver function, nor was amyloid found in the bone marrow, kidney or liver. After one year of continuous therapy with melphalan and prednisone, the patient's renal function has not worsened. We conclude with a review of the clinical and physiopathological features of the light chain subgroup of monoclonal immunoglobulin deposition diseases (MIDD).