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V Lederer

Publications and source records attributed to V Lederer.

16 recordsLinked to original sources

Betamethasone sodium phosphate injection: high-dose regimen in septic shock.

An intravenous bolus of betamethasone, at an approximate dosage of 3 mg/kg, was administered to 20 patients with septic shock. Treatment was repeated every four to six hours for periods ranging from 18 to 64 hours. Concomitant therapy included antibiotics in all patients and surgery in 10 patients. An additional patient underwent surgery after the conclusion of therapy. Clinical improvement was apparent within four hours after initiation of study medication in 14 (70%) patients. In the remaining six patients, improvement was observed no later than eight hours after the initial dose of the study agent. Reversal of shock was achieved in all patients, at which time treatment was discontinued. Tolerance to the study medication was excellent. No local or systemic adverse effects occurred.

Adult↗

[Metabolic disorders and current treatment of the surgical patient with pancreatitis].

Very frequently in acute and chronic pancreatitis, the surgical treatment is indispensable. The disease itself is accompanied by metabolic disturbances, protein deficiency, hepatic lesion, by diabetes and malabsorption syndrome. Following the laboratory parameters we were able to perform partial or total hyperalimentation, correction of acid-base dis-equilibrium and to obtain the positive nitrogen balance, and in this way keep the patients in optimal conditions pre- and postoperatively.

Acute Disease↗