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Biomedical subjects

V M Didenko

Publications and source records attributed to V M Didenko.

18 recordsLinked to original sources

[Spiral autovenous mesocaval shunt in portal hypertension syndrome].

The H-shaped mesenteriocaval shunt with the autovenous transplant was made in 22 patients with the intrahepatic form of portal hypertension. An original method developed by the authors was used. Two patients died after the operation. The rest of the patients were found to have decreased portal hypertension, retained hepatopetal circulation along the portal vein, no encephalopathy and no recurrent bleedings from the varicose veins of the esophagus.

Esophageal and Gastric Varices↗

[Esophagogastric bleeding as a complication of isolated thrombosis of the splenic vein].

The literature data and original experience (11 relevant cases) have provided evidence in support of marked diagnostic benefit of ultrasonography and transcutaneous transhepatic portography employed in suspected esophagogastric hemorrhage due to isolated thrombosis. Splenectomy and disconnection of pathological portocaval shunt through short gastric veins present surgery of choice.

Adult↗

[Late results of ligation of the splenic artery and its embolization in portal hypertension syndrome].

From study of the results of exclusion of the spleen in 87 patients with portal hypertension by ligation of the splenic artery (47) or its truncal embolization (40) with a Gianturko-type spiral, the authors conclude that in some cases these operations reduce portal pressure, manifestations of hypersplenism, and risk of bleeding, but do not guarantee that they will not develop. Ligation of the splenic artery or its truncal embolization is justified as an independent operative intervention when decompression anastomoses cannot be formed or the risk of their performance is extremely high.

Adolescent↗

[Characteristics of thrombocyte aggregation properties in portal hypertension syndrome complicated by esophagogastric hemorrhage].

An investigation of ADP-induced aggregation of thrombocytes in 62 patients with the portal hypertension syndrome has revealed pronounced functional alterations of blood platelets characterized by a lower aggregation rate, lower rate and degree of thrombocyte deaggregation. More profound alterations were found in patients with cirrhosis of the liver. It was established that the decreased rate and degree of the thrombocyte deaggregation with the growing aggregation rate, change of the aggregation into the irreversible form is a very dangerous portent of gastrointestinal bleeding.

Esophageal Diseases↗

[Infectious complications after splenectomy in patients with cirrhosis of the liver].

Based on an examination of 105 patients with cirrhosis of the liver with the syndrome of portal hypertension complicated by gastroduodenal bleedings who were subjected to splenectomy (in 86 patients there were proximal splenorenal anastomoses) the authors make a conclusion that infectious complications in the postoperative period in the group under analysis were developing against the background of the concomitant and predisposing conditions and can be compared in their incidence with infectious complications after other similar in severity operative interventions on organs of the abdominal cavity. In remote terms after operation the normalization of the indices of both cellular and humoral immunity was noted.

Adult↗

[Late treatment results in patients with portal hypertension complicated by gastroesophageal hemorrhages].

Under study were long-term results of the treatment of 356 patients with the syndrome of portal hypertension complicated by gastroesophageal bleedings. Various surgical interventions were performed on 147 of them. The authors made a conclusion that the selective "drainage" of the portal system (splenorenal anastomosis) had a number of advantages as compared with its total shunting.

Adolescent↗

[Dynamics of the cellular and humoral immunity indices before and after closed commissurotomy].

The state of the cellular and humoral immunity was studied in patients with acquired valvular disease of rheumatic etiology who were subjected to closed commissurotomy. It was established that the patients whose postoperative course was complicated by a suppuration of the wound had low levels of T-lymphocytes, immunoglobulins in their peripheral blood in the postoperative period. A dramatic elevation of the content of immunoglobulins of all classes on the 7th day of the postoperative period is considered to be the evidence of the development of an infectious process.

Adult↗

[Certain factors increasing the risk of local infectious complications following closed mitral commissurotomy].

Under analysis was the course of the postoperative period in 216 patients subjected to closed mitral commissurotomy. The risk of local infectious complications was found to be higher in patients with the IVth stage of mitral stenosis having lymphopenia, hypopotassemia, hyponatremia, hypochromic anemia, higher ESR in the postoperative period who had malaria and infectious hepatitis in the medical history.

Adolescent↗

[Evaluation of the blood coagulating system in acute gastroduodenal hemorrhages by thromboelastographic data].

Coagulation properties were studied thromboelastographically in 76 patients with acute gastroduodenal hemorrhages due to ulcerous disease of the stomach and duodenum, hemorrhagic gastritis and Mallory-Weiss syndrome. A certain regularity was revealed, i. e. the more profuse the hemorrhage the more frequent hypocoagulation associated with high fibrinolysis rate. With this in view transfusion therapy should be aimed not only at the replacement of circulary blood bolume but also at the suppression of high fibrinolytic activity of blood.

Acute Disease↗