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Biomedical subjects

V M Makhov

Publications and source records attributed to V M Makhov.

17 recordsLinked to original sources
PubMed1996

[Visceral lesions in alcoholism].

Rich clinical material has been gained on carbohydrate and lipid metabolisms, cardiovascular, hepatic, pancreatic, gastric parameters in chronic alcoholics. Functional and morphological changes correlated with duration of chronic alcoholism. No definite relationship existed between the stage of alcoholism and alterations in laboratory and instrumental findings in the course of abstinence syndrome.

Alcoholism↗
PubMed1992

[Functional intestinal dyskinesias].

The authors relate the results of examining 120 patients with functional disorders of the colon. The majority of the patients manifested diverse mental abnormalities of the neurotic origin, represented by different patterns of mental pathology, somatized disturbances, neuroses and psychopathies. The conditions favouring the origin of neurotic and functional disorders have been elucidated. It is concluded from the comparison of different treatment modalities that psychotherapy may be preferred.

Age Factors↗
PubMed1991

[Psychosomatic correlations in patients with functional disorders of the colon].

Basing on comprehensive clinical investigations of 50 patients with colon dysfunction, relevant somatic and psychological aspects have been analysed. Colon dysfunction in shown to attend neurotic and personality disorders, to be in some cases a somatoform manifestation of endogenic depression. The majority of the patients had psychogenic neurotic affections closely related to colon dysfunction which is considered a psychosomatic pathology.

Adolescent↗
PubMed1990

[The gastrin-producing function of the stomach in patients with chronic alcoholism].

Basal and maximum gastrin levels were measured in 81 patients with various stages of chronic alcoholism and different periods of alcohol intake, in 23 patients with chronic gastritis of nonalcohol etiology, and in 12 normal subjects. The findings permit a conclusion on the depressive effect of alcohol on the function of gastrin-producing G-cells, this resulting in lowered levels of both basal and maximal gastrin. A direct correlation between the degree of alcohol depression of gastric gastrin production and the length of alcohol consumption was revealed.

Adult↗
PubMed1987

[Hepatopancreatic syndrome in chronic alcoholism].

The results of puncture biopsy of the liver, ultrasonic and angiographic investigation of the liver and pancreas in 114 patients with chronic alcoholism revealed an increment of changes in these organs in parallel with an increase in the duration of chronic alcoholic intoxication. A simultaneous study of immunoreactive insulin (IRI) and C-peptide showed that an increase in the IRI basal level in the patients suffering from alcoholism up to 10 yrs was determined mainly by an increase in the activity of beta-cells. In a long period of alcoholism an increase in the IRI basal level resulted from a decrease in the rate of insulin degradation in the liver as assessed by a lower level of C-peptide. In liver cirrhosis a noticeable decrease in pancreatic incretory function was combined with noticeable disturbance of insulin degradation in the liver. The above investigations showed that there were morphological, functional and clinical signs of the "hepatopancreatic syndrome" in chronic alcoholism.

Adult↗
PubMed1984

[Morphology and morphogenesis of chronic gastritis in patients with alcoholism].

The characteristics of all types of chronic gastritis in patients with chronic alcoholism is given. Alterations of the stomach mucous membrane in alcoholism of different duration are described in detail. The intermediate type filaments in the surface epithelium, cells of glands and macrophages are found which is reported to be a morphological manifestation of alcoholism.

Adult↗