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V M Panchenko

Publications and source records attributed to V M Panchenko.

85 records · Page 5Linked to original sources
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[Fibrinogen degradation products, soluble fibrin and antithrombin III in toxic goiter patients].

A total of 31 patients with toxic goiter of various severity were investigated; the blood and urine content of the products of fibrinogen and fibrin degrading (PFD), of soluble fibrin, antithrombin III, fibrinogen and fibrinolytic activity were studied. There was a marked elevation of PFD content in the blood and their normal content in the urine, an increase in soluble fibrin level, and fibrinolysis activation. Hyporegulation revealed in patients with toxic goiter is apparently connected with increased fibrin degradation, and is secondary in character.

Adolescent↗
PubMedDate not supplied

[The effect of piyavit on hemostatic processes and fibrinolysis in patients with ischemic heart disease].

The oral use of the drug Piavit (derived from freeze-dried medicinal leeches) in 50 patients with coronary heart disease for 7 days in a daily dose of 600 mg (20 patients) and 1200 mg (30 patients) caused a moderate dose-independent increase in enzymatic, fibrinolysis, non-enzymatic fibrinolysis and antithrombin III activity. In half the patients who had low fibrinolytic levels, the agent stimulated mainly the release of plasminogen activator on administration days of 2 and 7. In other 15 patients the activity of plasminogen activator remained unchanged, but non-enzymatic fibrinolysis enhanced. Piavit prolonged the hypocoagulative effect of heparin and aspirin in the group of patients pretreated with these drugs. There were no clinical manifestations of the disease during 7 days.

Aged↗
PubMedDate not supplied

[Effect of docanol on the status of hemostasis and fibrinolysis systems, as well as lipid spectrum in patients with ischemic heart disease depending on the initial level of fibrinolytic activity].

Forty patients with coronary heart disease (CHD) concurrent with hyperlipidemia were divided into 2 groups according to the baseline fibrinolytic activity. The group with the depressed fibrinolytic system displayed the highest atherogenicity index and levels of cholesterol, low and very low density lipoprotein cholesterol and half levels of high density lipoproteins. After 45-day ingestion of docanol, a new Russian food additive containing docosahexanoic and eicosapentaenoic acids there were positive changes in the lipid spectrum in the both groups. The fibrinolytic changes were heterodirectional: activator and plasma activities increased in the group of fibrinolytic depression while in the group of baseline normal fibrinolysis the activity of plasminogen activator fell.

Aged↗