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Biomedical subjects

V Macionis

Publications and source records attributed to V Macionis.

12 recordsLinked to original sources
PubMed2001

A local adhesive finger splint.

A new design of a local static finger splint is proposed. The splint is made by enveloping a length of wire into double-sided adhesive tape. The skin of the region to be immobilized is covered with an adhesive skin dressing, to which the splint is then adhered. This method of attachment gives more freedom in choosing a site of splint application and prevents access obstruction to the wound, blocking of tactile areas, and circulation impairment. The splint is light, low profile, and malleable at ambient temperature. The adhesive splint was used in 5 patients to maintain the first web space open or to immobilize stiff interphalangeal joints in flexion overnight.

Adhesives↗
PubMed2000

Termino-lateral neurorrhaphy: the functional axonal anatomy.

The goal of this study was to determine the functional axonal anatomy of a termino-lateral neurorrhaphy (TLN). We hypothesize that axons populating a TLN must relinquish functional connections with their original targets prior to establishing new connections via the TLN. Two-month-old F344 rats underwent a TLN between the left peroneal nerve and a nerve graft tunneled to the contralateral hindlimb. Three months postoperatively, an end-to-end neurorrhaphy was performed between the nerve graft and the right peroneal nerve. Four months after the second operation, contractile properties and electromyographic (EMG) signals were measured in the bilateral hindlimbs. Left peroneal nerve stimulation proximal to the TLN site resulted in bilateral extensor digitorum longus (EDL) and tibialis anterior (TA) muscle contractions, with significantly lower forces on the side reinnervated by TLN. Evoked EMGs demonstrated that the right and left hindlimb musculature were electrically discontinuous following TLN. These data support our hypothesis that axons can form functional connections via a TLN, but they must first relinquish functional connections with their original targets.

Anastomosis, Surgical↗
PubMed2000

New protective system preventing self-mutilation of rat surgical sites.

The paper presents a new approach to the rat self-mutilation mechanism, and introduces an appropriate protective system. Observations revealed that rats use three main implements to damage experimental sites, i.e., their teeth, forelegs, and hind legs. Ignoring even one of these factors diminishes the reliability of a protective system. Commonly used rat vests sometimes fail, since free fore- and hind legs may damage the system itself or the surgical area directly. A new system was designed to avoid these problems. A splint is glued to the fur of the rat neck and chest with fast-bonding glue, to prevent flexing the neck. Then, a vest is fabricated by wrapping adhesive tape around the chest and neck. One of the forelegs is immobilized by incorporating it into the tape vest. The action of the hind legs is neutralized by taping the feet with toes flexed. Such a protective system design is more reliable than those previously proposed, since teeth, forelegs, and hind legs are all prevented from self-mutilation. In addition, the tape vest and mittens fit the rat body well, and are easy to apply.

Animals↗
PubMed2000

Clamp delay: an effective new method of nonsurgical delay.

This study introduces an effective new method of nonsurgical delay. In this new method, a special clamp that compressed a bipedicled skin fold along the sides of a proposed flap was glued to rat dorsa. The study also used a control group of untreated flaps and a group of flaps delayed by the conventional surgical procedure involving conventional parallel incisions. Eight days later, 1 x 6 cm reverse McFarlane flaps were isolated from the wound and raised. After 5 days, the survival length of the flaps was measured. Viability of the flaps delayed by the clamps [40.5 +/- 2.0 mm (mean +/- standard error); n = 10] did not differ from that of surgically delayed flaps (41.3 +/- 3.6 mm; n = 8) and was significantly higher (p < 0.001) than the survival of control flaps (26.3 +/- 0.6 mm; n = 10). Clamp delay can be useful in flap research that explores the relative significance of the vessel obstruction and biochemical processes that follow the surgical delay procedure. This method also offers a new perspective by introducing the concept of nonsurgical delay into clinical practice.

Animals↗
PubMed1999

Dorsolateral toe flap as a neurovascular graft carrier in finger reconstruction.

Simultaneous finger nerve and artery grafting, and soft-tissue coverage with a dorsolateral toe flap, including a plantar digital neurovascular bundle, were performed in a single patient. Although only fair sensory recovery was achieved, due to complicated wound healing, the toe flap as a neurovascular graft carrier can be a treatment of choice for reconstructing complex finger palmar defects.

Adult↗
PubMed1998

Heel replantation.

A 14-year-old boy presented with oblique amputation of the heel through the calcaneum. The heel fragment was successfully replanted but the postoperative course was complicated by venous insufficiency requiring further venous anastomosis and attributed to tension in the skin closure.

Adolescent↗
PubMed1997

Reversed free osteoarthrocutaneous dorsalis pedis flap for simultaneous reconstruction of the trapeziometacarpal joint and the first metacarpal bone.

Simultaneous reconstruction of a traumatic defect of the trapeziometacarpal joint and the first metacarpal with a composite dorsalis pedis flap is described. The transplant, consisting of the second metatarsal and the second metatarsophalangeal joint, was reversed at the defect site for the metatarsophalangeal joint to become a new trapeziometacarpal joint. A long vascular pedicle was necessary for direct micro-vascular anastomoses to the radial vessels at the wrist. This transfer can be expected to be effective in reconstructing composite hand defects involving the trapeziometacarpal joint and the entire first metacarpal bone.

Adult↗
PubMedDate not supplied

Skin preservation at a supraphysiologic temperature and induction of epithelial cysts by subcutaneous grafting: attempts to simplify evaluation of storage media and of graft viability.

This pilot study used a new experimental rat model designed to explore whether in-depth investigation of the following two questions would be reasonable: (1) Can skin storage media be faster evaluated by storing skin at a supraphysiologic temperature, and (2) can evaluation of skin graft viability be facilitated by subcutaneous grafting leading to production of epithelial cysts from the viable portions of the grafts? The experiment involved skin storage at 47.3 degrees C in saline and in 10% Dextran 40 solution for periods ranging from 0 to 18 min, followed by subcutaneous grafting. The surface area of the resultant epithelial cysts and the cyst-to-graft ratio inversely correlated with storage time, which is in accordance with a well-established analogous relationship involving the rate of graft 'take'. The skin tended to remain viable longer in Dextran 40 solution, which is consistent with previous studies of low temperature storage demonstrating superiority of high-molecular-weight solutions. The results warrant further investigation of the above issues.

Animals↗