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Biomedical subjects

V Marinov

Publications and source records attributed to V Marinov.

At least 19 recordsLinked to original sources
PubMed1990

[The detection of metastases of ovarian carcinoma by immunoscintigraphy with monoclonal antibodies].

Sixty eight women, operated for ovarian carcinoma, were studied by monoclonal antibodies anti-CA-125 labeled with 131I. 99m-Tc was used for the scintigraphy. Ninety-one metastases were discovered as 73 of them were established surgically. 52/61 were confirmed in the pelvis, 19/24 in the abdominal cavity and 3/6 in the liver. Higher precision of immunoscintigraphy was found in the diagnosis of liver metastasis, when it was compared with echographic and computed tomographic examinations.

Adult↗
PubMed1990

[The pathomorphological changes in the pleura of rabbits with artificial pneumothorax and uropolin pleurography].

The results from artificial pneumothorax in 25 rabbits with intrapleural administration of Uropolin (10 rabbits) as well as of 10% solution of NACl (7 rabbits) were described. Thoracotomy was made on 7th, 14th and 12 21st day and the parietal, diaphragmatic and visceral pleura with underlaying tissues were examined. Proliferation of the mesothelium [correction of mesother] and growth of the connective tissue, which were more manifested in rabbits treated with Uropolin, were established histologically. The authors think that pathohistological examinations confirm the clinical observed favourable effect of intrapleural administration of Uropolin for obliteration of the pleural cavity.

Animals↗
PubMed1989

[The immunoscintigraphic diagnosis of the metastases of colorectal cancer by using monoclonal antibodies].

Sixty-four patients operated for colorectal cancer comprise the study group. CEA and CA-19.9 markers were used. The antibodies were labelled with 131I, using for the scintigraphy 99mTc as well. Eighty eight metastatic foci were detected, 67 of them (76.1 per cent) confirmed by the surgeon: Of 55 pelvic localizations, surgically detected were 47 (85.5 per cent), of 24 in the abdominal cavity 15 (62.5 per cent) were confirmed and of 9 in the liver--only 5 (55 per cent). Radioimmunoassay more accurate in pelvic localizations, whereas echography and computer tomography were more precise in liver examination (83.3 per cent).

Adult↗
PubMed1989

[The role of the laser in gastrointestinal surgery].

In a series of 2500 operations with laser in the gastrointestinal region the authors used laser CO2 with up to 90 W strength and Nd--Yag with up to 80 W strength, both alone and in combination. Principal application of this technique is in oncologic surgery: resection of liver, volatilization of hepatic and other metastases, destruction of inoperable carcinoma in the middle and distal portion of the rectum and in other fields of proctologic surgery. In this aspect, laser technique is a powerful palliative means in the general arsenal of surgery.

Digestive System Surgical Procedures↗
PubMed1989

[Diagnostic and therapeutic problems in typhoid fever complicated by severe enterorrhagia (apropos a patient successfully treated by surgery)].

The case history of a 69-year-old patient with typhoid fever is described. The disease ran an atypical course; with early jaundice syndrome, severe enterorrhagia and late appearance of roseola. He was successfully treated by surgical intervention--hemicolectomy. The need of surgical treatment of patients with typhoid fever, who have severe, life-threatening enterorrhagia, is emphasized.

Acute Disease↗
PubMed1988

[Effect of various factors on total serum cholesterol based on the data from an epidemiologic study in 4 large communities of Bulgaria].

The study includes 6243 persons--4051 women and 2192 men, mean age 37.9 +/- 14.2 years. The total serum cholesterol was examined and the factors related to the cholesterolemia were studied. A strong statistical correlation was found between the cholesterolemia and age, sex, body mass, smoking, degree of physical activity, alcohol consumption, feeding and diabetes mellitus. This multifactorial correlation of cholesterol serum level determines the need of complex population measures for reducing the high cholesterol level by correction of the mode of feeding and living and counteraction of the harmful habits (smoking), overfeeding, physical hypodynamia.

Adult↗
PubMed1984

[Electron microscopic study of the liver after experimentally resecting it and covering its surface with BAPP and BAPK].

An analysis of data of electron microscopic investigations of liver preparations within the terms of from 7 to 425 days after resection of the liver in which the liver wound was covered by the antimicrobial polycaproamid gauze made in Bulgaria has shown that the polymer material does not cause alterations in the liver structure and cell organelles of hepatocytes not preventing regeneration of the liver.

Animals↗