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V Meier

Publications and source records attributed to V Meier.

25 records · Page 2Linked to original sources

[Hematuria in Schistosoma mansoni bilharziosis].

Following a stay of a few months in Africa, a 9 year old boy developed gross hematuria, dysuria and pollakisuria. Two urine cultures remained sterile, the intravenous urography was normal. Therefore a tropical disease was looked for. Eggs of Schistosoma mansoni in the urine sediment, a significant level of schistosomal antibodies, and blood eosinophilia proved our suspected diagnosis of schistosomiasis to be correct. An ultrasonic examination of the urinary tract showed a thickened bladder wall. Very unusual in this case is the primary infection of the bladder with Schistosoma mansoni which normally affects the intestine.

Child↗

[Cytostatic pneumopathy following chemotherapy for metastasizing breast neoplasm].

A 69-year-old patient treated with anticancer polychemotherapy for metastatic breast carcinoma died of respiratory distress and cardiac failure 3 months after commencement of therapy. At autopsy only a few pleural micrometastases were found. Microscopic study revealed early lung lesions due to cytotoxic drug treatment. While the earlier literature described different lesions associated with different antineoplastic drugs (busulfan, bleomycin), today there is more emphasis on the common pathological features. Therefore, instead of the expressions "busulfan lung" or "bleomycin lung", we suggest the use of the term "Zytostatika-Pneumopathie" (cytostatic drug induced lung disease).

Aged↗

[Significance of mitochondrial DNA for forensic stain analysis, identification and forensic lineage determination].

DNA testing using conventional STR systems may produce insufficient results, if the genomic DNA in the specimen is either highly degraded or the available quantity is very small (e.g. skin particles, hair shafts or ancient bones). In some of these cases the examination of mitochondrial DNA, which is present in considerably larger copy numbers in the cytoplasm, is more successful than that of nuclear DNA. Identification of unknown corpses by conventional DNA typing sometimes remains doubtful, if only samples from presumably distant relatives or putative brothers or sisters are available for comparison. Since mitochondrial DNA is generally transmitted in maternal lineages, its sequence pattern can be directly compared with those of other individuals and, in case of the same maternal lineage, corresponding sequence chromatograms are to be expected. In connection with nuclear DNA typing methods certain sequence motives may furnish clues to ethnic groups. The report presents three cases illustrating the application possibilities of mtDNA typing in forensic practice.

Adolescent↗