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V Meininger

Publications and source records attributed to V Meininger.

122 records · Page 7Linked to original sources
PubMed1976

[Dendroarchitectonic study of the inferior colliculus in the cat].

A network analysis of dendritic fields of the cells of the inferior colliculus has been performed in the adult cat. The cells of the dorso-medial nucleus have a smaller volume, less terminal segments and more dendritic spines than the cells of the ventral lateral nucleus. The bifurcation ratio of the different cells makes it possible to separate two different types of cells: order 2 cells with a strictly monochotomous branching on random segment and order 3 cells which dendrites grown by terminal branching on random pendant arcs.

Animals↗
PubMed1976

[Facial paralysis with inverse autonomic-voluntary dissociation from a frontal lesion. Cortical origin. Relation to supplementary motor area].

As a result of 6 cases of frontal tumour presenting central facial paralysis with inverse dissociation this symptom was investigated in patients subjected to cortical excisions for intractable epielpsy. A study of 8 cases of frontal cortical excision, 6 of them affecting the internal and posterior portion, and two the prefrontal region, has provided evidence of a link between inverse automatic-voluntary dissociation facial paralysis and lesions affecting the Penfield supplementary motor area. In such cases, facial palsy is usually associated with motor disorders in the limbs, the most characteristic of which is unilateral motor under-utilisation. The possibility of inverse dissociated facial paralysis occurring as a result of a rostral premotor lesion cannot be ruled out in our present state of knowledge.

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PubMed1976

[Dendroarchitectonic study of the pyramidal cells of the medial frontal cortex of the macaca].

A comparative study of "normal" and "improperly oriented" pyramidal cells has been performed in the medial frontal lobe cortex of the monkey (Macacus Irus). The comparison of the observed number of topological types for each group of dendrites shows that the apical dendrites of each type of cells have a different growth. The apical dendrites of the normal pyramidal cells grow by monochotomous branching on random segments and have much more spines on the first order segments, the apical dendrites of the improperly oriented pyramidal cells grow by branching on pendant arcs (terminal growth model), and have fewer spines. The functional signification of these differences remains actually obscure.

Animals↗
PubMed1976

[Comparative study of the dorso-medial nucleus of the inferior colliculus].

The comparative study by network analysis of the dorso-median nucleus of the inferior colliculus has been performed in the adult and new born cat, the adult rat and the adult monkey. For each animal, the two previously recognized types of cells have been identified. However the number of each type of cells is different. The 2 order cells have the same volume in the rat, the adult cat and the monkey. The 3 order cells are larger in the monkey and the cat than in the rat. The number and the volume of the different types of cells is similar in the ventro-lateral nucleus of the adult cat and in the dorso-medial nucleus of the new born cat.

Animals↗
PubMed1976

[Meningeal arterio-venous fistulas with cortical venous drainage].

Pure dural arteriovenous fistulas are still not properly understood, and pose problems wich are far from being resolved. Among these, dural fistulas with cortical venous drainage represent a very special entity since they alone are expressed clinically by a neurological brain syndrome. Diagnosis is difficult and mistakes can be made as it is only by means of hyperselective arteriography of the branches of the external carotid that an accurate diagnosis can be made. However, their diagnosis assumes considerable importance since surgical or radiological treatment of hese fistulas brings about complete disappearance of clinical symptoms.

Adult↗
PubMed1975

[Scanning transmission electron microscopy of dendritic spines stained by the Golgi method].

Scanning transmission electron microscopy of the dendritic spines of multipolar neurons in the cat inferior Colliculus was achieved on Golgi semi-thin sections. The three basic types of dendritic spines (ST, MS, TH) were identified. Scanning transmission electron microscopy provides a reliable method for a three dimensional view of these structures at high resolution and consequently a more accurate appreciation of their size. In addition, it could prove very useful in the quantitative analysis of the dendritic spines.

Animals↗
PubMed1975

[Arteriovenous fistulae of the dura mater. Clinical and radiological study of 13 cases].

The authors studied 13 new cases of fistulae of the dura mater. With reference to these 13 cases, and to the literature, they propose a classification according to the type of drainage of the fistula: direct, into a dura mater lake, into a cortical vein. This clasification enables a better clinical and radiological approach to these anomalies.

Dura Mater↗
PubMedDate not supplied

Motor consequences of motor area ablations in man.

Motor disorders reported in the present paper do not result from cortical ablations stricto sensu since some white matter was excised in every patient. However they appear to suggest that, as suggested by Walshe (1935), the central region and premotor area are a functional entity, i.e. they work as a whole. The extensive lesions of the premotor area, leaving untouched the motor region, have the same motor and tonic consequences as lesions limited to the central region. This point which appears specific for man does not imply that the premotor region subserves activities similar to those subserved by the central region. Rather it may suggest a deafferentiation of the central region, the consequences of which would be more important than is generally assumed. Extensive central or premotor lesions determine various tonic disorders: a well known spasticity, with exaggeration of the stretch reflex, associated with an increase in passive swinging of segments of limbs and in extensibility of joints. These two latter phenomena are usually defined as hypotonia. With premotor and precentral lesions the hypotonia disappears and a hemiplegic posture is observed. This hemiplegic posture is a dystonia which apparently does not result directly from the exaggeration of the stretch reflex. Anatomically it appears to result from lesions of both central and premotor regions. This is in agreement with Denny-Brown's (1966) contention that an extrapyramidal region lies rostral to the prerolandic sulcus. As suggested by Evarts (1973) motor regions appear to control automatic as well as voluntary movements. They probably play a role in the trophic function of muscle, since, despite rehabilitation, amyotrophy was present in every case reported in the present paper.

Adolescent↗
PubMedDate not supplied

[Tolerance of riluzole in a phase IIIb clinical trial].

Within the framework of an early drug access programme launched in 1995, a multicentre open study was initiated in France in order to assess, inter alia, the safety of riluzole (50 mg twice a day) in a total of 2069 patients from 28 centres. This programme, a phase IIIb study with direct individual benefit, had two main objectives: to enable patients to receive riluzole therapy pending regulatory approval and commercial availability and to provide further data on the safety of riluzole in a broader ALS population. The most frequent adverse events related to riluzole treatment were: asthenia, nausea and elevation of serum transaminase levels. These observations, similar to data derived from previous pivotal clinical trials, confirm that riluzole has a satisfactory tolerability profile.

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