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V Melichar

Publications and source records attributed to V Melichar.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Protein metabolism in the small for gestational age newborn in relation to the severity of fetal malnutrition].

The daily nitrogen balance, the amino acid concentrations in serum and urine, and the bile acid concentrations in the serum on the eighth day of life were estimated in newborn infants small for gestational age with different degrees of fetal malnutrition. The amino acid concentrations in urine and serum as well as the total nitrogen losses by urine increase in dependence on the severity of fetal malnutrition. In addition the bile acid concentrations were elevated whereas the urea concentrations in serum remained unchanged. These results point to a deranged liver function which depends on the degree of fetal malnutrition. These special metabolic conditions have to be considered in the nutrition of such infants. The bile acid concentrations seem to be an efficient parameter to estimate this metabolic situation.

Amino Acids↗
PubMed1985

Nutrition of newborns small for gestational age with human milk lyophilisate enriched human milk during the first week of life.

In 24 very low birth weight infants appropriate or small for gestational age, the metabolic response to nutrition with human milk lyophilisate enriched human milk was estimated during the first week of life. In contrast to newborns appropriate for gestational age, in newborns small for gestational age signs of metabolic overloading could be observed: increased urinary amino acid excretion and neonatal cholestasis. Both depended on the degree of fetal growth retardation. It was concluded that nutrition with human milk lyophilisate enriched human milk cannot be recommended for very low birth weight infants during the first week of life. In newborns small for gestational age the metabolic situation has to be estimated before starting a high protein diet. If the level of total bile acids amounts to more than 30 mumol/l, protein intake should be increased carefully during the first week of life.

Amino Acids↗
PubMed1979

[Nitrogen balance in premature babies during parenteral nutrition (author's transl)].

This paper represents a continuation of research into the nitrogen (N) balances in seriously premature babies. During parenteral nutrition an increased amount of 400 mg N/kg body weight/24 hrs. was administered in the form of L-aminoacids together with glucose and fat emulsion. No change in the amount of retained aminoacids occurred (some 80%). On the other hand several increased values of N-metabolites demonstrate that this dosis of aminoacids can be considered as the maximal value.

Dietary Proteins↗
PubMed1978

[Nitrogen balances in very premature newborns in the course of parenteral nutrition (author's transl)].

Nitrogen balance studies were performed in the course of parenteral nutrition during the first 5 days of life in 2 groups of premature newborns (I. group: 7 prematures, b.w. M = 1295g; II. group: 7 prematures, b.w. M = 1447g). Glucose and fat emulsion were administered intravenously in children of the first group, in the second one L- Aminoacids (250 mg N/kg body weight/24 hrs.) were added. In comparison with the first group nitrogen retention of 77 to 170 mg/kg body weight/24 hrs. was reached, but blood urea concentration increased significantly.

Birth Weight↗
PubMed1977

The effect of fructose infusions in the course of labor upon parturient and fetus.

Fructose infusions were administered to parturients with healthy term fetuses at a speed of 1 g/min for 106 on the average. The results confirm that fructose has the expected properties. The blood glucose and FFA levels show that a substantial part of the infused fructose is indeed stored and that only a small portion is used to cover immediate energy needs. This positive result is predominant by a considerable degree of acidosis arising in the parturient in spite of the fact that fructose was infused at a slower rate than in the majority of papers published so far. Since the fructose infusions were intended for premature fetuses, which already have an increased tendency toward acidosis, the results confirm the unsuitability of such a treatment.

Blood Glucose↗