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V Melichercíková

Publications and source records attributed to V Melichercíková.

6 recordsLinked to original sources

Problems associated with sterilization using ethylene oxide. Residues in treated materials.

The paper deals with problems associated with reduction of undesirable effects of ethylene oxide in polymers in medical devices on the patient's health. The authors explain the need of careful elaboration and validation of the sterilization and aeration process incl assessment of ethylene oxide (EO) residues. The authors investigated the effect of the type of material and conditions of sterilization and aeration on the assessed EO concentration. For research of the behaviour of different polymers in the sterilization process model sterilizations of actual items of medical devices with a known composition proved more suitable than assessment in medical devices from medical institutions. The main conclusions of the investigation were a classification of polymers into those suitable and unsuitable for sterilization or resterilization, and attention was also drawn to poor reproducibility of results in old sterilizers, in particular those lacking effective aeration in aerators.

Acrylates↗

New disinfectants.

The authors estimated the microbicidal effect of disinfectants produced by the firm Henkel Austria, namely Spitaderm, Incidin M spray, Incidur, Incidur spray, Sekusept pulver, Sekusept forte and Maranon H. The aim of the study was the verification of the effectivity of preparations and the proposal of their application in Czechoslovak practice. The estimation was performed in two stages: in vitro and in practice. The standard suspensive method, the suspensive micromethod and the method of carriers were chosen for the experiments, as well as the strains of grampositive and gramnegative bacteria, the spores of B. subtilis, yeasts and the model virus. In the second part of experiments, the disinfectants were applied according to the producer's instructions in inpatient departments of internal medicine and of surgery at the University Hospital in Olomouc in the course of 4 weeks. During the experiment, the rubdowns were taken twice a week from the working places, floor, instruments and hands and the bacterial contamination of the establishment was estimated. In hemodialysing centre, the apparatuses of the artificial kidney were estimated as well, as the preparation Maranon H is recommended for their disinfection. The results of the experiments show that the recommended concentrations of disinfectants and their effective exposition are chosen with sufficient safety coefficient. In chosen wards, the minimum bacterial contamination was observed. All disinfectants were accepted favourably, their scent estimated as pleasant, the staffs evaluated their high cleaning properties and the dosage equipment, ensuring the precise concentration of preparations. With regard to the above mentioned results, the authors recommend to start the licensed production, as all the tested preparations correspond to the exigent demands of modern and effective disinfection.

Bacteria↗

Disinfectant effect of Persteril in combination with detergents.

In laboratory conditions, the microbicidal effect, pH and changes in the content of peracetic acid and hydrogen peroxide were tested in Persteril at concentrations of 5 ml/l and 0.5 ml/l as well as in mixtures of these Persteril solutions with the detergents Jar, Pur, Hit, Corona, Sapon, Rekord and Universal. The efficiency and stability of Persteril solution in combination with the detergents were similar to those of Persteril aqueous solution. The tested mixtures ensured satisfactory bactericidal effect after 19-day storage. The sporicidal effect could be guaranteed during 5 days only at a concentration of 5 ml/l and provided disinfection was carried out by submerging. The above mixtures of Persteril and detergents have been recommended for one-stage disinfection in all types of medical facilities requiring simultaneous disinfection and washing.

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