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Biomedical subjects

V Mendes

Publications and source records attributed to V Mendes.

At least 19 recordsLinked to original sources
PubMed1994

[Anatomo-clinical aspects of ganglionic tuberculosis in Senegal: comparative study between the 60's and 80-90's apropos of 139 cases].

The authors report the results of a retrospective and comparative study of anatomo-clinical aspects of ganglionic tuberculosis carried out over two periods of five years each: first period: 1962-1966; second period: 1988-1992. This study shows a higher prevalence of this disease among children during the first period with an odd ratio of 4.36. In the second period, young adults are the most affected particularly the age group between 30 and 39. The possible role of the HIV virus in this phenomenon has been pointed out. The most common histological forms were the subacute ones with a distinct prevalence during the second period, on the opposite of the acute and chronic forms.

Adult↗
PubMed1994

[Ovarian pregnancy apropos of 2 cases].

The authors report 2 cases of ovarian pregnancy at Gynecological Obstetric Clinic of University Teaching Hospital in Dakar out of 210 ectopic pregnancy registered in a 28 month period (March 91 to June 93). These are the fourth and fifth cases operated on in Dakar (the 3 first cases are reported during the last 10 years). In light of the 2 cases using the data of the literature, the authors try to find out the particularities of the scarce affection which etiopathogeny is still unclear even if the symptomatology is often similar to a tubal pregnancy. The diagnosis is often evoked during laparatomies but its confirmation is based exclusively on the anatomopathological test. The frequent existence of intra ovarian hematoma and zones of necrosis make people practise annexectomy which should be avoid as much as possible.

Adult↗
PubMed1991

[Apropos of hepatorenal polycystic disease associated with cirrhosis].

The authors report a case of association of cirrhosis with (autosomal dominant) polycystic kidney and liver disease, which is hereditary malformation. The occurrence of hepatic cysts during the disease is relatively common, and the development in general is benign. In this case, the large hepatic cysts are responsible of biliary ducts compression, with clinical and biological cholestasis. Portal hypertension like impaired hepatocellular function develop because of cirrhosis.

Cysts↗
PubMed1991

[Congenital serous cyst of the orbit with anophthalmos].

The authors reported a case of orbital congenital serous cyst with anophtalmos. It was a third type of Duke Elder classification. Although it looked sporadic, this malformation is hereditary and due to a disharmony between optic cup growth and differenciation. Ultrasonography and scanner could confirm the diagnosis and helped to discard orbital and eyelid angioma and meningocele. After excision, a prosthesis must be adapted in the orbit.

Anophthalmos↗
PubMed1990

[Dermoid of the cornea. Report of 2 cases of Ida Mann's 2nd type].

At the opposite of epibulbar dermoids (which are isolated or combined), dermoids of IDA MANN's second type are uncommon. The two cases reported had a big size and covered almost the cornea, without damage on the descemet's membrane, the endothelium and the other eyeball structures. This lesion is classified by the W.H.O. among choristomas. It's made of skin recovering fat which includes in different figures, hair follicle, eccrine and sweat glands. Total excision is the best treatment, but couls become complicated by cornea perforation. It could be followed in some cases by keratoplasty. Amblyopia could go with this malformation.

Cornea↗
PubMed1989

[Problems with carotid chemodectomas].

The authors report on their initial observation of a Shamblin Type I carotid body chemodectoma. Surgical exeresis was complete and relatively easy even though the diagnosis has been carried out in the open air. They take the opportunity to discuss diagnostic, therapeutic, evolutional and nosological problems connected with this rare neoplasm.

Aged↗
PubMed1989

[Fibrous histiocytoma of the orbit].

The authors reported a case, a large orbital fibrous histiocytoma, in a 14 year old girl. They emphasize nosologic problems and histologic aspects of this benign tumor. Because of the localisation and the size of the tumor, a double anterior orbitotomy (superior and inferior) was necessary for complete renoval. Anatomic, functional and esthetic results were satisfactory.

Adolescent↗
PubMed1984

Bone ultrastructure and x-ray microanalysis of aluminum-intoxicated hemodialyzed patients.

In hemodialyzed patients aluminum (Al) intoxication may induce osteomalacic lesions which are mainly observed when plasma immunoreactive parathyroid hormone (iPTH) concentrations are low, and osteitis fibrosa absent. In this study, the bone tissue of eight hemodialyzed patients with elevated plasma and bone Al concentrations was examined by histomorphometry, electron microscopy, and x-ray microanalysis. Five patients (group 1) had osteomalacia and minimal osteitis fibrosa, three patients (group 2) had severe osteitis fibrosa. In group 1, Al was concentrated at the mineralizing front, in hexagonal structures measuring 200 to 1,000 A which also contained phosphorus, but not calcium. Hydroxyapatite needles had a normal aspect. Osteoblasts appeared inactive. In group 2, Al was also present at the mineralizing layer of osteoid, but, in these cases, in small clusters next to abnormal calcium deposits. Osteoblasts appeared very active. Their mitochondria contained calcium and phosphorus granules, or amorphous material, measuring 1,500 to 2,000 A, emitting x-rays characteristic for Al and phosphorus. These results suggest that secondary hyperparathyroidism, by stimulating the cellular activity, may increase the uptake and release of Al by the osteoblasts. The presence of Al within the mitochondria of these cells may be one of the factors inducing the mineralization defect.

Adult↗
PubMed1984

[Hyperparathyroidism secondary to renal insufficiency: anatomo-clinical relations and the potential role of an aluminum overload].

Severe secondary hyperparathyroidism is still observed at present in 5-10% of haemodialysis patients. It requires surgical correction. Fifty-eight haemodialysis patients had neck surgery and their 222 parathyroid glands analysed. The individual gland weight was comprised between 22 and 3880 mg (mean +/- SEM, 689 +/- 62 mg). Mean total parathyroid gland weight per patient was comprised between 2 and 3 g. Schematically, 4 types of gland architecture could be distinguished: diffuse hyperplasia alone; diffuse hyperplasia associated with incipient nodule formation; hyperplasia with pronounced nodule formation; and nodule formations alone. Total gland weight was significantly higher for the latter two histological forms than for the former suggesting transformation with time of pure hyperplasia to nodular hyperplasia. Patients with chronic pyelonephritis had a mean gland weight higher than that of patients with chronic glomerulonephritis (3308 +/- 498 mg versus 1824 +/- 358 mg, p less than 0.01). No relation was found between total gland weight and plasma calcium, phosphate or alkaline phosphatases. However, a weak relation existed between total gland weight and plasma immunoreactive parathyroid hormone. In addition, a negative relation was observed between highest prior plasma aluminium and gland weight when considering only patients with a gland weight less than 2000 mg. Parathyroid gland aluminium content was significantly higher in haemodialysis patients than in nonuraemic patients with primary hyperparathyroidism. A direct relation was found between parathyroid gland and bone aluminium. In conclusion, in haemodialysis patients with evolving hyperparathyroidism initially diffuse gland hyperplasia appears to be associated progressively with nodule formation. Circulating immunoreactive parathyroid hormone is positively related to total gland weight.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1983

Secondary hyperparathyroidism in chronic haemodialysis patients: a clinico-pathological study.

Fifty-eight patients on intermittent haemodialysis underwent parathyroidectomy because of severe secondary hyperparathyroidism. Mean individual parathyroid gland weight was 689 +/- 62 (SEM) mg. Mean total gland weight per patient was between two and three grams. Increasing nodule formation within hyperplastic glands appeared to develop with increasing time of duration of hyperparathyroidism. Patients with chronic pyelonephritis had a higher gland weight than those with chronic glomerulonephritis. A direct relationship was found between gland weight and circulating immunoreactive parathyroid hormone, but an inverse relationship between gland weight and plasma aluminium concentration. The higher the parathyroid gland aluminium, the higher was the bone aluminium concentration.

Adolescent↗