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Biomedical subjects

V Miletić

Publications and source records attributed to V Miletić.

At least 19 recordsLinked to original sources
PubMed1979

Distribution of four IgG Gm antigens in different experimental IgG samples.

The distribution of four Gm antigens was determined in rivanol-soluble as well as in chromatographically obtained human IgG preparations. In rivanol-soluble IgG, enrichment in IgG3 carrying Gm5 antigen was demonstrated and, in a preparation fractionated by DEAE-Sephadex chromatography, molecules with a predominantly Gml-expressed antigen were shown to be present.

Animals↗
PubMed1977

[Immune hemolytic anemia and thrombocytopenia after peroral therapy with a penicillin derivative (phenoxymethylpenicillin)].

A previously apparently healthy male patient developed Coombs-positive haemolytic anaemia and thrombocytopenia during phenoxymethylpenicilline intake. A drug dependent IgG red cell antibody was demonstrated in patient's serum. In vitro tests with patient's serum suggested formation of complexes involving penicilline which by complement mediated mechanisms were able to agglutinate red cells in saline medium. Platelet agglutinins were demonstrated in patient's serum but their drug dependence has not been fully elucidated. The mechanism of drug mediated autoantibody synthesis might have been involved in the pathogenesis of thrombocytopenia.

Adult↗