[Current aspects of pulmonary granulomatosis].
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Biomedical subjects
Publications and source records attributed to V Moisescu.
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Two indicators are of primary importance in the assessing the tuberculous endemia in a determined area: the prevalence of bacilliferic sources, especially of those that have been confirmed by bacteriological examinations (bacterioscopy), and the annual incidence of the tuberculous infection (the real infection risk). Possibilities are described, and examples provided, for approximation of the incidence of the tuberculous infection through: a) conversion index; b) the ratio between the prevalence of the tuberculous infection and the median tested age; c) the Styble-Meijer-Sutherland logarithmic ecuation; d) the nomogram variant with tables B and C established by Styblo-Meijer-Sutherland; e) the R. Narain graphic methods. For those countries in which BCG vaccination is practiced on an extensive scale the authors suggest the incidence risk indice could also be calculated, for supra-infection, which can be correlated and completed by the incidence (risk) of infection.
In view of differentiating post-vaccinal allergy from that developing after tuberculosis infection, the authors have investigated comparatively intradermal-reactions to tuberculin according to classical allergometry, and to the 4 types described by Palmer-Edwards in a group of 1549 students and 211 patients. All the subjects were tested with 2 units of PPD IC 65. It was noted that the type I and II Palmer reactions corresponded, in the majority of the cases, to intense, or hyperergic ID reactions, while the types III and IV of Palmer corresponded to slightly positive, or to negative ID reactions. The presence of the post-vaccinal scar does not appear to influence significantly the type of the reaction, but the presence of active specific lesions is accompanied by reactions of type I and II of the Palmer classification. It is concluded that although the Palmer types do not allow to make a clear differentiation between the two variants of allergy they provide however useful indications for the interpretation of IDR in a more sophisticated manner, as compared with the conventional allergometry.
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An analysis is made of the tuberculous endemia in several of the most important industrial branches over the last years, as compared with the endemy outside the industrial environment. Although the global morbidity through tuberculosis in industrial enterprises has declined to approximately one half of the initial values (considering the year 1975 as the basis), it is still above the level in the territory. The gap between the two curves, much wider at the beginning of the interval, has narrowed consistently with time. The factors are discussed, that may determine this relative morbidity, and the necessary measures for their neutralization. The necessity for a close cooperation is stressed, between the enterprise physician and the pneumologist (or phthisiologist) from the territorial polyclinic.
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Prosthesis use in surgical repair of abdominal wall is becoming nowadays a worldwide method, being imposed by its efficiency in solving the defects. The authors are speaking in the light of their experience gained with 100 patients that underwent the operation of prosthesis implant inside the abdominal wall between 1990 and 1996. There have been correlated the early and late postoperative results with some features of this surgical procedure (see below), to prove its efficacy. The authors discuss some principles of alloplastic treatment, which represent also the conclusions of the study: the moment of when a prosthesis is recommended, the choice of synthetic material, where and how is placed the prosthesis, some additional measures which contribute to therapeutic success.