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Biomedical subjects

V N Anders

Publications and source records attributed to V N Anders.

7 recordsLinked to original sources

[Ultrastructural features of cerebral synapses in schizophrenic patients].

The paper is concerned with ultrastructural traits of synapses in the frontal lobe, supraoptical nucleus of the hypothalamus and caudal nucleus of the brain in 12 schizophrenic patients and 8 normals (the period of autopsy was 4 hours following death). The results demonstrated 2 types of changes: 1) slightly expressed changes (a decrease of the extent of active zone contacts, changed forms in the synaptical vesicles); 2) extremely expressed or degenerative changes in the synapses (an appearance of fibrillar structures, glycogene granules, degeneration of synaptical endings of a dark type).

Brain

[Electron-cytochemical distribution of acetylcholinesterase, monamine oxidase and Mg2+-ATPase in the human hypothalamus].

The distribution of acetylcholinesterase, monoaminoxidase and ATP-ase was studied in human hypothalamus by means of electron microscopy. The study demonstrated a possibility of differentiation of the hypothalamic neurons according to phases of neurosecretion. These data were achieved on the basis of electron cytochemistry in detecting ATP-asa in the nuclei of neurons. Comparing literary data concerning the nonmediator role of acetyl-choline and catecholeamines with personal studies, the authors demonstrate the internal and external barrier functions of acetylcholinesterase and monoamineoxidase in the brain.

Acetylcholinesterase

[A quantitative assessment of enzyme activity by cytophotometry using a standard].

The usage of the standard has been offered in cytospectrophotometrical measurements of enzymatic activities that are revealed histochemically. A tetrazolium method was used to demonstrate lactate dehydrogenase activity in sections of the rat brain. As a standard, a mixture of the enzyme (a crystalline forme of LDG) and gelatine was taken. The method of standardization permits fulfilling a quantitative comparison of heterogenic biological materials.

Animals