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Biomedical subjects

V N Andreev

Publications and source records attributed to V N Andreev.

At least 19 recordsLinked to original sources

[Diagnosis of fractures by sound].

For the purpose of objective evaluation of the sound diagnosis the authors have generalized an experience of application of four methods of the acoustic diagnosis of bone fractures. There have been compared the efficiency of the auscultatory percussion method, the method of its objectivization by means of measuring devices, the sound diagnosis method, following the pattern of auscultatory percussion and self-sustained oscillation measuring method. There have been noted the high efficiency and up to 98% coincidences with clinico-roentgenologic data in case of application of the sound diagnosis method with the self-sustained oscillation systems.

Adolescent↗

[Obtaining and rearing germ-free miniature piglets for biomedical research].

The method of obtaining and rearing germfree miniature piglets for medical-biological research is described. The gnotobiotes were reared in rigid organic glass isolation cells up to 3 months. Milk diets supplemented with minerals and vitamins were used for nutrition. The gnotobiotes gained weight well during the whole observation period.

Animal Husbandry↗

[Opsonizing activity of the serum of gnotobiotic guinea pigs contaminated with individual representatives of intestinal microflora].

The influence of contamination of germfree guinea pigs with individual representatives of the intestinal microflora (Bac. mesentericus, Bac. subtilis, S. albus, and S. faecalis) on the formation of the serum opsonic activity was studied. An increase of the opsonic activity to all the microorganisms on the 11th day after a corresponding monocontamination and a stimulating influence of the serum on the intracellular digestion of Bac. mesentericus and Bac. subtilis microbes was noted. As to the pathogenic microorganisms (E. coli 055), S. Faecalis only were capable of stimulating the serum opsonic activity. The results indicated the presence of an association between the microflora composition and the opsonic activity of the animal blood serum. The value of this index also depended on the properties of the phagocytosis object.

Animals↗

[Effect of contamination of germ-free guinea pigs by individual representatives of the intestinal microflora on antibody and complement concentrations].

On the 3rd day after birth germ-free guinea pigs were contaminated with one of the following representatives of normal intestinal microbial flora: Bac. mesentericus, Bac. subtilis, S. albus, and S. faecalis. In the animals aged two weeks a study was made of the level of antibodies against the microorganisms used for monocontamination, and also to the E. coli O55 pathogenic for guinea pigs; the complement content in the serum was examined as well. Bac. mesentericus and Bac. subtilis contamination of guinea pigs altered the antibody content to these microbes but insignificantly, whereas S. albus and S. faecalis stimulated the antibody genesis considerably. Similar results were obtained in respect to E. coli O55. The complement level was markedly stimulated by the spore aerobes and S. albus.

Animals↗