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Biomedical subjects

V N Blagodarov

Publications and source records attributed to V N Blagodarov.

At least 19 recordsLinked to original sources

[The characteristics of the morphofunctional restructuring of the aortic endothelium in food-related atherosclerosis and hyperadrenalinemia].

Morphofunctional reorganization was studied of endothelium during the stage of formation of alimentary atherosclerosis and in experimental hyperadrenalinemia using transmission electronic microscopy and histochemistry together with silver nitrate impregnation of aortal endothelial monolayer. Certain morphofunctional equivalents have been established for the vascular wall exposure to the above factors, indicative of their unequalability and possibility of potentiation under combination. In both cases, an interrelationship similar in character has been shown between intensity of the endothelial reciprocal response and its regional morphofunctional features.

Animals↗

[Changes in the bioenergetic processes and immunoglobulin transport in the stomach tissues of rats after vagotomy].

Data are reported on changes of bioenergetic processes and immunoglobulin transport in gastric tissues after bilateral subdiaphragmatic transsection of the vagal nerves. It was established that the mucosa and muscle membrane of the stomach showed a reduced activity of the glycolysis enzyme. There was also abnormal transport of autogenic immunoglobulins, namely increased penetration of immunoglobulins into the connective-tissue stroma of the mucosa and the surface of epithelium into the gastric cavity. The protein transport into the endomysium of the muscle membrane was sharply reduced. It is concluded that the above mentioned changes reflect development of neurogenic dystrophy after vagotomy.

Animals↗

[Kidney ultrastructure in experimental lithiasis and nephrocalcinosis].

An experimental electron-microscopic study of the kidneys was carried out in experimental oxamide nephrolithiasis in rabbits and hypervitaminosis D in rats. The most pronounced changes were revealed in the proximal and the distal convoluted tubules. It is suggested that cytosomes and lysosome-like bodies possibly participated in stone formation and nephrocalcinosis. It is supposed that they played an important role in the morphogenesis of nephrolithiasis man.

Animals↗