[Morphofunctional characteristics of the lungs in experimental mycoplasmal and pneumococcal infection].
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Biomedical subjects
Publications and source records attributed to V N Chebotkevich.
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The effect of 3-hydroxyanthranilic acid-antigen on peripheral blood leukocyte migration inhibition was studied in 75 patients with bladder malignancies. The antigen appeared to modify the said migration. A correlation was established between stage of tumor progression and the effect of 3-hydroxyanthranilic acid-antigen on leukocyte migration.
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A method for production of a reference lyophilized preparation for diagnosis of Mycoplasma pneumonia infections in the indirect hemagglutination (IHA) test has been developed. The method is based on conjugation using bi-diasotized benzidine of acrolein-treated sheep erythrocytes and ultrasonicated whole Mycoplasma antigen. After lyophilization the diagnostic preparation retained its standard properties for 1.5 years (the observation period). The sensitivity of the preparation in detection of antibody exceeded those of the CFT and the metabolism inhibition (MI) test 16--64-fold and the specificity was as good as in these tests. The diagnostic value of the preparation in the IHA was 78.1%, in the CFT--64.7%. As compared with the CFT and the MI test, the IHA with Mycoplasma diagnostic preparation is simple and reproducible.