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Biomedical subjects

V N Efimov

Publications and source records attributed to V N Efimov.

At least 19 recordsLinked to original sources

[The respiratory center--the regulator of the respiratory system].

The authors consider the respiratory centre to be the regulator of the respiratory system and to consist of 3 main functional blocks: chemoregulator, respiratory rhythm autogenerator and mechanoregulator, functions of which are provided by the neurons of medulla oblongata. The main aim of chemoregulator block is to maintain the level of ventilation volume speed, which is necessary to compensate the difference between the signals of setting and the firing from the chemoreceptors. The main aim of mechanoregulator block is to provide the functioning of the regulation loop of the respiratory muscles comparing the signals which come from the respiratory autogenerator, and the firing of the mechanoreceptors. The generator unit of the respiratory centre is a set of rhythm-forming associations, the system of 4 neurons (early and late inspiratory and expiratory) are typical among them. The neurons are connected by recurrent inhibitory bonds: the neuron of each rhythm-forming group, successively becoming excited, inhibits the two preceding neurons in the cycle; for all this the neuron of the successive group is released from inhibition and in such a way the rhythmogenesis occurs. The respiratory centre forms a common unit for chemo- and mechanoreceptor loops, through which the circuits of feedback for both loops are connected, providing the regulation of breathing.

Animals↗

[Actual problems of surgical treatment of patellar fractures].

The article analyzes an experience with the operative treatment of 90 patients with fractures of the kneepans and injuries of the extension system. A combination of the kneepan suture with a thorough suture of the lateral extension system and restoration of the anatomical form of the articulation surface of the kneepan in young and middle aged people allows the functional treatment to be started earlier, and in elderly and senile patients it made the deformity less by the improvement of motor activity and early movements. Recommendations for technical fulfilment of the operation are given.

Adult↗

[Possible modes of autorhythmic activity of a single neuron].

The rhythmic impulse activity of the nerve cells is one of the characteristic phenomena often registered in the experiments on different objects. According to the nature of its origination it should be distinguished the evoked rhythmic activity from autonomic. The variants of interaction of pacemaker and membrane oscillators leading to the variety of regimes of autorhythmic activity of the neuron are discussed. The interaction of several membrane oscillators without the participation of the pacemaker autogenerator may lead to the authorhythmic reverberative (extracellular) activity.

Action Potentials↗

[Allogeneic tendoplasty in surgery of the locomotor system].

Allogenic tendotransplants were used in the treatment of different lesions and diseases of the locomotor apparatus in 410 patients. Good anatomical and functional results were obtained in 84% of the patients. Unsatisfactory results were noted in 7% of cases. The method of preservation of allogenic tendons had no influence upon the results.

Arm Injuries↗

[Allotendinoplasty in knee joint injuries].

The experience of surgical treatment of 51 patients with fresh and old injuries of the knee joint is analyzed. The operation consisted in plastic of the integrity of the injured patella, extension apparatus, cruciate ligaments of the knee joint. Allogenic tendinous transplants of musculus peroneus longus, extensor of the foot toes, flexor of fingers conserved by freezing were used. Good results of the treatment were obtained in 43 patients, satisfactory-in 5 and unsatisfactory-in 3 patients.

Female↗