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Biomedical subjects

V N Gavrilin

Publications and source records attributed to V N Gavrilin.

10 recordsLinked to original sources
PubMed2001

[Interaction of artificial carbon-mineral sorption preparations with the wound content].

The surface of SUMS1 was studied using scanning electron microscopy after contact with the wound contact. In vivo sorbent action was found to differ from in vitro adsorption properties of sorption drugs, as during the contact with organism tissue in the inflammation focus granule active surface is covered by fibrin, to which necrotic tissues, bacteria and immunocompetent cells adhere. The use of sorption drainage in acute and chronic inflammation lowers the challenge on lymphatic tissue because removal of sorption preparations also causes elimination of large fragments of non viable tissues, antigens and protein-cellular conglomerates that might block lymphatic vessels and regional lymph nodes.

Cellulitis↗
PubMed1996

[The valves of the marginal sinus of the lymph nodes].

Popliteal lymph nodes of male Wistar rats were studied in scanning regime of electron microscope. On the base of the data obtained it is concluded that on the lymph node surface and in the thickness of a capsule afferent lymphatic vessels branch into thin rami supplied with valves from the inside of the capsule in the site of falling into marginal sinus. Valvular apparatus found obviously gives possibility to regulate lymph flow in the lymph node.

Animals↗
PubMed1991

[Structural changes in the lymph node sinuses in acute blood loss].

By means of light and scanning electron microscopy sinuses of the popliteal lymph nodes have been studied in 50 Wistar male rats. After modelling of an acute hemorrhage in the animals (in 15, 120 min and 1 day) volume of the medullary and marginal sinuses increases essentially, while blood stream intensity decreases in peripheral tissues. Amount of fenestrae in the sinusal lining decreases, that is, perhaps, caused by edema of cytoplasm in the lining cells and accompanied with formation of numerous cytoplasmic protrusions into the sinusal lumen. In 3 days the blood stream level in the peripheral tissues restores, structural organization of the littoral cells in the lymphatic sinuses normalizes. The data obtained demonstrate that during the first day after the acute hemorrhage decrease of hematolymphatic exchange intensity in lymph nodes and enhancement of transitory lymph flow in them take place.

Acute Disease↗
PubMed1985

[Structural organization of the compensation process in the lymph nodes in venous stasis].

Transmission and scanning electron microscopy was used to study the structural organization of the lymph nodes during venous congestion. At the early period (1 h of venous congestion) one could see an increased number of the fenestrated cells in the venous part of the capillary whereas at the later period (after 6 h to 3 days) a rise of the microvesicular transport via endotheliocytes of the arterial part of the capillary and via fenestras of the venous part. Within 7 to 14 days one could see activation of the microvesicular transport via the indicated parts of the capillary. At all the stages of venous congestion the fluid contained by the parenchyma of the lymph node penetrates via fenestras and intercellular fissures to the marginal sinus, while only via fenestra to the cerebral sinuses.

Adaptation, Physiological↗
PubMed1985

[Littoral cells of the lymph node sinuses in venous congestion based on scanning electron microscopic data].

The littoral cells of the sinuses in the popliteal lymph nodes have been studied in Wistar rats under physiological conditions of hemodynamics and 1 h after ligation of the caudal vena cava. Intercellular clefts (1-4 mcm wide) are demonstrated to exist between the littoral cells of the internal wall of the marginal sinus. Presence of fenestrae in the peripheral thinned areas of cytoplasm is specific for these cells. The diameter of the fenestrae is 60-1,000 nm however, the fenestrae with the diameter up to 100 nm predominate. Lining of the medullar sinuses is also characterized by a high content of fenestrae, the maximal diameter of the fenestrae being the same as in the marginal sinus, although most of the fenestrae have the diameter 50-500 nm. No open intercellular clefts between the littoral cells of the medullar sinuses are revealed. In some cases, penetration of lymphocytes through the lining of the sinuses is observed. Under venous congestion, the diameter and amount of the fenestrae, size and amount of open intercellular clefts in the lining of the lymphatic sinuses increase significantly. This demonstrates its increasing permiability, having an essential importance for compensation of circulatory disturbances in the zone of the venous congestion.

Animals↗
PubMed1983

[Ultrastructure of the endothelial cells of blood capillaries of lymph nodes in the rat].

Ultrastructure of endothelium in the rat popliteal lymph nodes has been studied. The cross section area of the capillary arterial part is 29.9 +/- 1.0, that of the venous part -- 91.2 +/- 1.6, the luminal cross section of the arterial part is 4.90 +/- 0,23, that of the venous part -- 46.8 +/- 1.1 mcm2. Nucleous-cytoplasmic ratio in the endotheliocytes of the arterial part is 1.50 +/- 0.06, that of the venous part -- 2.10 +/- 0.13. The number of microvesicles per 1 mcm of the profile length in the section of the basal surface in a plasmolemma is 1.13 +/- 0.07 both in the arterial and venous parts of the capillary, that of the luminal surface -- 1.35 +/- 0.07 for the arterial part and 0.48 +/- 0.03 for the venous part. The number of free microvessels per 1 mcm2 of the cytoplasmic cross section area is also greater for the arterial part (9.6 +/- 0.8 vs. 7.3 +/- 0.4 in the venous part). Numerical density of free ribosomes in endotheliocytes of the arterial part is 62 +/- 6, in the venous part -- 47 +/- 5 per 1 mcm2 of the cytoplasmic cross section. Numerical density of mitochondria in the venous part is 0.77 +/- 0.11 and in the arterial part -- 0.40 +/- 0.04 per 1 mcm3 of cytoplasm.

Animals↗
PubMedDate not supplied

[A morphological analysis of the results of using the capron drainage-tampon with a sorbent for the treatment of acute nonspecific metroendometritis].

The surface of carbon-mineral sorbent (CMS-1) granules and that of the capron cartridge were investigated using scanning electron microscopy in the course of acute nonspecific metroendometritis treatment after late abortion. The use of this sorbent for drainage of the uterine cavity decreases a toxic and antigenic effect on the organism. The use of the capron cartridge excludes the loose of the sorbent granules and their contact with the tissues, does not hinder the drainage and, at the same time, capron serves as a filter preserving active granule surface from a rapid disactivation by large fragments of tissue detritus.

Abortion, Spontaneous↗