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Biomedical subjects

V N Golubev

Publications and source records attributed to V N Golubev.

At least 19 recordsLinked to original sources
PubMed1987

[Bombesin reduces body temperature chiefly by increasing peripheral blood flow].

Bombesin, some of its fragments and analogues, being injected intracerebroventricularly, induce rapid decline in body temperature. The active fragment of bombesin--C-terminal nonapeptide--induced a 25% depression of oxygen consumption in cold-exposed rabbits, no changes in the shivering thermogenesis, and a 3.5--5.0-fold increase of ear blood vessels section area accompanied by a gain in linear velocity of blood flow. The peripheral blood flow seems to be the main effector of the bombesin-induced hypothermia.

Animals↗
PubMed1984

[General patterns of the sensory processes in exposure to extreme stimuli].

A series of changes in sensory sphere take place in conditions of extremal and unusual influences. These changes are determined directly by processes at the receptor level and indirectly--by the central interaction. In spite of great variety of the influences, there are some general laws in changes of functional state of afferent systems analogous to biophysical and neurophysiological processes. The evaluation of functional state of sensory systems in such conditions can only proceed on ergonomic base taking into consideration the sensory fatigue as well.

Central Nervous System↗
PubMed1981

[Prolonged-action gentamycin sulfate eyedrops].

A new dosage form of gentamicin, 0.3 per cent eye drops with polyglucin was developed. Its pharmacokinetics and chemotherapeutic properties were studied. It was shown that in the form of eye drops gentamicin has a prolonged action, provides high levels of penetration into the eye tissues and is effective in the treatment of eye infections.

Animals↗
PubMed1977

[Antibodies to thyroglobulin in patients with cancer].

Investigations of over 300 oncological patients and 120 healthy individuals have evidenced a considerable increase in the frequency of detecting antibodies to thyreoglobulin (in the titre 1/80 and higher) in patients with cancer of the breast, sigmoid and stomach in females and a tendency to such increase in cancer of the uterine body, and a number of other localizations.

Adult↗