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Biomedical subjects

V N Grebeniuk

Publications and source records attributed to V N Grebeniuk.

At least 19 recordsLinked to original sources
PubMed1990

[The diagnostic importance of research on the lysyl oxidase activity in children with circumscribed scleroderma].

Blood serum lysyl oxidase activity considerably varies, these variations correlating with the skin process dissemination, in children suffering from focal scleroderma. This enzyme was undetectable in normal subjects and patients with dermatoses whose clinical symptoms are similar to those of focal scleroderma. Blood serum lysyl oxidase activity elevation is a specific sign, characteristic of patients with focal scleroderma; it therefore may be used for the laboratory diagnosis of this dermatosis, assessment of its dissemination and severity.

Adolescent↗
PubMed1990

[Recombinant human alfa2-interferon (reaferon) in ointment form in the treatment of various diseases of the skin and mucosa].

Clinical trials of the gene engineered human alpha 2-interferon as ointment were performed. The ointment was used in the treatment of patients with relapsing herpes of various localization, relapsing aphthous stomatitis and pemphigus vulgaris. It was shown that the ointment was harmless and its therapeutic effect was favourable. The preparation is recommended for introduction into the practice of public health.

Adult↗
PubMed1990

[The copper content of the blood and skin in children with circumscribed scleroderma].

The authors have demonstrated the pathogenetic significance of elevated copper levels in the blood and involved skin in development of collagen metabolism disorders in children suffering from focal scleroderma. A correlation between elevation of blood serum copper level and the skin process dissemination and activity was revealed. Copper concentration in involved skin of these children surpassed 7-fold the normal value.

Adolescent↗
PubMed1990

[The clinico-dermatological and morphological characteristics of the hair involvement in children with chemical poisoning].

A syndromal condition, transitory neuropsychic symptoms and signs of catarrhal inflammation of upper respiratory tract mucosae and alopecia, develop in children with symptoms of chemical poisoning due to exposure to heavy metal salts. Electron microscopy shows changes that evidence a high incidence of dying and dead hair. Alopecia was more frequently subtotal and there was a tendency to hair growth restoration after the cause of the condition was removed and prophylactic measures carried out.

Child, Preschool↗
PubMed1989

[Atopic dermatitis as a term and a disease].

Basing on the literature data and their own clinical experience, the authors consider atopic dermatitis as skin manifestations of hereditary atopic constitution. They distinguish 5 clinical forms of the condition, emphasizing the age succession (phase pattern) of the clinical and morphologic picture of the dermatosis. Attention is called to the fact that atopic dermatitis may be a part of the clinical picture of many syndromes. The authors hope that the present discussion will minimize the confusion in the terminology of this disease.

Dermatitis, Atopic↗