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Biomedical subjects

V N Guzenko

Publications and source records attributed to V N Guzenko.

5 recordsLinked to original sources
PubMed1993

[Results of surgical treatment of patients with coral-shaped kidney stones].

The results of treatment of 140 patients with coral-like renal calculus operated on with blockade of the renal blood flow and performance of pharmacologic protection of a kidney have been analysed. The possibility to remove all the fragments of a coral-like calculus under favourable conditions (on a "dry" organ, performance of nephrotomy with low traumaticity and minimal blood loss) was noted. This allowed early restoration of renal function and 17% decrease in the incidence of the development of recurrent calculus formation.

Drug Therapy, Combination↗
PubMedDate not supplied

[Primary hyperparathyroidism in patients with bilateral nephrolithiasis].

Experience in the diagnosis and treatment of the renal form of primary hyperparathyroidism in 57 patients with bilateral nephrolithiasis was summed up. The main diagnostic criterion was the detection of biochemical changes in the blood and urine (hypercalcemia, hypophosphatemia, hypercalciuria) and the use of some tests (Howard's test and parathyroidin test). Parathyroidectomy was performed after establishing diagnosis. A new stage in therapy of such patients was a study of renal function and phosphocalcium metabolism after parathyroidectomy. The improvement of some indices (an increase in glomerular filtration, urea excretion with urine and relative urine density, and a decrease in hypercalciuria and hyperphosphaturia) indicated the effectiveness of surgical intervention for primary hyperparathyroidism in patients with bilateral nephrolithiasis. It was also confirmed by a decrease in lithogenic relapse after parathyroidectomy.

Arteries↗
PubMedDate not supplied

[The morphofunctional changes in the kidneys of patients with staghorn nephrolithiasis operated on using a block of the renal blood flow].

A study was made of morphofunctional changes in the kidneys depending on duration of ischemia and use of the drug combination proposed by the contributors to the article, for pharmacological protection of the kidney. The examination of intraoperative renal biopsy specimens revealed the hystological structure of the kidney to be more intact, with its functional capacity tending to restore more readily than in control, in those patients in whom pharmacological protection had been embarked on. Constricting the renal artery and carrying on pharmacological protection of kidney we succeeded in effecting a complete elimination of the coral-like calculus fragments in favourable conditions on a "dry" organ, being able to manage with almost non-traumatic nephrotomy associated with minimum loss of blood, which fact resulted in the reduction of the lithogenesis recurrence rate by 17 %.

Animals↗