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Biomedical subjects

V N Iakovlev

Publications and source records attributed to V N Iakovlev.

At least 19 recordsLinked to original sources
PubMed2004

[RAPD fingerprinting of common bream Abramis brama L., roach Rutilus rutilus L., and their F1 hybrids].

The polymerase chain reaction with arbitrary primers (RAPD-PCR) was used to study and to evaluate the genetic variation in the hybrid progeny of two Cyprinidae species, common bream Abramis brama and roach Rutilus rutilus. Genetic polymorphism was studied in 20 fishes (young of the current year) obtained in four individual crosses: R. rutilus x R. rutilus (RR), A. brama x A. brama (AA), R. rutilus x A. brama (RA), and A. brama x R. rutilus (AR). Amplification spectra obtained with eight primers contained 288 fragments, 97.6% of which proved to be polymorphic. The proportion of polymorphic fragments was 75.0% in the RR progeny, 58.1% in the AA progeny, 84.9% in the AR progeny, and 77.8% in the RA progeny. Classification analysis in the space of principal components was performed with the first four components, which together accounted for 64% of the total variance of the character under study. The individual contributions of components I, II, III, and IV were 26.8, 16.8, 11.5, and 8.9%, respectively. Fishes of the two pure species and the hybrid progeny (direct and reverse hybrids together) were clearly differentiated in the space of principal components I and II. The best differentiation of the four samples (RR, AA, RA, and AR) was observed in the space of principal components II and IV. Possible causes of high genetic variation in interspecific hybrids are discussed.

Animals↗
PubMed1995

[Acute pneumonia as a problem of hospital infection].

The article is about an acute pneumonia which develops in weak patients in nosocomial conditions. The authors study the question of secondary pneumonia, its etiology, systematization, diagnosis and treatment including application of immunocorrectors.

Acute Disease↗
PubMed1993

[The characteristics of the clinical picture, immunological indices and treatment of patients with acute pneumonia in sensitization of the body].

The peculiarities of the clinical picture in acute pneumonia in patients with sensibilization of an organism (pronounced rhino-conjunctival syndrome and more prolonged hyperthermic reaction in acute period, frequent aggravations of allergic process) require application of antiallergic therapy. Depending on the character of immunopathological reactions the complex treatment can be provided using administration of desensibilizing drugs, medications of non-specific desensibilization, natrium chromoglicate, corticosteroids, and sometimes plasmapheresis and hemosorption.

Acute Disease↗
PubMed1993

[The clinico-functional results of aortocoronary bypass in patients with ischemic heart disease and their medical rehabilitation].

Using the materials of foreign researches the article provides data concerning the modern methods of rehabilitation of cardiological patients taking into account its efficiency for various age groups. Operation on heart itself is a psychological shock to the patient. It needs adequate psychological adaptation and corresponding medical care. 300 patients with ischemic heart disease were under the authors' observation after aortocoronary shunting (age 31-69). Clinical and functional results were studied after operation. The results of early and late loading tests were analysed. Indication for hypolipidemic therapy were determined. The article reports on the errors in determining the proof loads and limitations in the correction of myocardial insufficiency. The authors substantiate the possibilities towards prognostication of the course of ischemic heart disease after operation.

Adult↗
PubMed1992

[Changes in the indices of the coronary amd myocardial reserves in myocardial infarct patients during rehabilitation].

The article analyses the results of the complex examination of 52 patients with large-focal and through-and-through myocardial infarction using veloergometry, echocardiography, tetrapolar rheography, diurnal ECG monitoring at cardioanalyzer. It was found out that veloergometry was more preferable in the late hospital period. Echocardiography was more preferable in the sanitary-polyclinic period for the young and middle-aged patients with through-and-through myocardial infarction, and at the late hospital period for elderly patients with large-focal and through-and-through myocardial infarction. In both periods described above echocardiography was effective in young and middle-aged patients with large-focal myocardial infarction. As for the volume of information obtained with the help of tetrapolar rheography and diurnal ECG monitoring it was equal in both periods.

Adult↗
PubMed1991

[Microscopy of the sputum in the etiological diagnosis of acute pneumonia].

The authors propose an algorithm for an early etiological diagnosis of pneumonia. The microscopy of Gram-stained smear of sputum is one of the main components of the algorithm. The character of microflora obtained as the result of the analysis determines the further medical examination and treatment of patient.

Acute Disease↗