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Biomedical subjects

V N Iarygin

Publications and source records attributed to V N Iarygin.

At least 19 recordsLinked to original sources
PubMed2006

[Spinal cord regeneration in rats after thoracic segmentectomy: growth and regeneration of nerve fibers].

As it was described in a previous paper (Morphology, 2005, v.127, Iss. 2), spinal cord (SC) consolidation after thoracic segmentectomy in rats took place via connective tissue scar formation in the area of trauma, which was accelerated when SC defect was filled with by the collagen gel (Spherogel). In this paper, on the basis of semithin section analysis and transmission electron microscopic study, it was shown that regenerating nerve fibers crossed the connective tissue within the formations, which were structurally identical to peripheral nerves. In the zones of rarified SC substance, caudally to the site of trauma, myelination of growing axons was realized by glial cells without the formation of the nerve truncs. In the white matter, within the fasciculi of SC lumbar segments, multiple thin regenerating fibers were seen in the area of degenerated myelinated nerve fibers.

Animals↗
PubMed2005

[Spinal cord regeneration in rats after thoracic segmentectomy: restoration of the anatomical integrity of the spinal cord].

Spinal cord (SC) segmentectomy was performed at ThX level in 28 rats. The scar formation in place of surgery and the degree of restoration of anatomical integrity were studied in control rats (group I) and in rats, in which SC defect was replaced by either Spherogel neuromatrix (group II) or Spherogel containing dispersed embryonic nerve cells (group II). While in group I rats by weeks 1-2 SC defect was filled with fibrin masses, in rats of experimental groups II and III the formation of connective tissue scar was found by the same time. By weeks 10-11 these animals demonstrated partial restoration of motion in three joints of the hindlimb. In the scar tissue and in adjacent SC zones numerous regenerating thin myelinated nerve fibers were found. They were clearly demonstrated in the zones of cranial and caudal borders along the whole distance until the appearance of typical tissue of SC. In slides from the animals of control group, thin myelinated nerve fibers were found only in close proximity to SC substance, while in the scar tissue and in the cellular bands of the intermediate zone nerve fibers were scarce.

Animals↗
PubMed1997

[Biomedical aspects of health preservation strategy: role of catecholaminergic neuronal populations].

Lifestyle, environmental factors, genetics, and medical care are the main factors that determine the health status of man. Of particular attention are biological mechanisms ensuring the body's adaptation to constantly changing environmental conditions. The noradrenergic neuronal populations, the sympathetic nervous system in particular, modulate metabolic processes and supports a variety of activities, making them relevant to changing living conditions. There is a clear correlation between the life span and the number of sympathetic nerve cells functioning during postnatal ontogenesis. The exposures that reduce the activity of peripheral and central noradrenergic neurons and slow down aging processes in them loosen the relationships between the inner and outer world to prevent hyperactivity and to prolong life.

Adaptation, Physiological↗