[Rapidly progressing clinical course of Burger's disease].
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Biomedical subjects
Publications and source records attributed to V N Kukushkin.
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A morphologic study of 376 hearts from individuals who died between 75 and 98 years of age demonstrated senile amyloidosis of the heart in 307 (82%) of the cases, using the Congo red stains for polarized light studies and the thiosine red for luminescent microscopy. The frequency of cardiac amyloidosis detection increased with age, and reached 100% in those above 90. Clinico-anatomical correlations showed repolarization changes to be the most common findings (80%), followed by arrhythmia (over 50%), conductivity disorders and reduced voltage of electrocardiographic waves. Chronic heart failure was less common (about 10%). In most cases, moderately marked coronary atherosclerosis was also found at autopsy. Amyloidosis was thought to be making a more significant contribution towards myocardial lesions, as compared to atherosclerosis, in elderly people above 85 years of age.
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The results of endoscopic and morphological diagnostic methods for gastric polyps in 91 patients are analysed in detail. It is concluded that endoscopic examination makes it possible to reveal gastric polyps of any localization. However, to solve the problem of therapeutic policy it is necessary to examine the biopsy material from polyps, prior to their removal, both cytologically and histologically. This is due to the fact that small size polyps after endoscopic polypectomy are no longer suitable for morphological assay, whereas cytograms obtained from the transverse sections and surface of large polyps are equivalent diagnostically to cytograms of the biopsy specimens.
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The role of a lethal issues analysis in improving the level of public health is discussed. The significance of autopsy results and their analysis, with the development of medical science, not only did not decrease but, on the contrary, considerably increased. Real possibility of computer analysis of the lethal issues appeared with the introduction of International classification of diseases. The requirements to the unified reports of the departments of pathology are considered, the latter being the most important information about the activity of the pathology service and the quality of the therapeutical and diagnostic process at its different levels.
The paper concerns the problems facing pathologic anatomy service in Moscow. It is stated that the service needs reorganization. The advances in methodology, staffing, continued training, salary system, connections with other services should be accomplished.