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Biomedical subjects

V N Molotkov

Publications and source records attributed to V N Molotkov.

At least 19 recordsLinked to original sources
PubMed1985

[Endolymphatic therapy in the combined treatment of patients with respiratory diseases].

Based on a study of the clinical efficacy of endolymphatic administration of antibiotics in 160 patients with different pulmonary diseases the methods of the use of endolymphatic therapy (ET) as part of a complex of therapeutic measures for lung abscess, pneumonia, chronic purulent bronchitis have been devised. The pharmacodynamics of gentamicin, brulamicin, pentrexyl, ketocef and claforan administered endolymphatically has been explored. Positive shifts have been demonstrated in cyclic nucleotides and immune responsiveness during ET, a constituent part of multiple modality treatment.

Adolescent↗
PubMed1984

[Role of medical cybernetics in the improvement of diagnosis, prognosis and choice of treatment method in pulmonological patients].

The authors review some aspects of the use of medical cybernetics methods in pulmonology. Analyze the results of machine and machine-free (mark) diagnosis of chronic lung diseases. Demonstrate that the quality of the disease recognition by means of the cybernetic methods correlates with that attained by highly specialized therapeutic institutions. Discuss the results of predicting the outcomes of the treatment of respiratory system diseases and the possibilities of using the mathematical methods for the classification optimization.

Cybernetics↗
PubMed1984

[Magnetophore therapy in the combined treatment of patients with obstructive bronchial diseases and its effect on immunological reactivity].

Follow up of 93 patients with chronic obstructive bronchitis and bronchial asthma enabled the authors to trace the effect of magnetophorotherapy combined with pathogenetic treatment on the disease progress, external respiration function, cardiovascular system, and immune responsiveness. It was shown that magnetophorotherapy is an effective therapy for bronchial obstruction, favouring the recovery and improvement of respiratory function, characteristics of the flow-volume curve. It also exerts a beneficial effect on different components of immunity.

Adolescent↗
PubMed1982

[Clinico-laboratory basis for the endolymphatic use of beta-lactam antibiotics in pulmonology].

Clinical efficacy and effect of cefuroxime, claforan and pentrexyl used endolymphatically were studied in 85 patients with acute abscess forming and persisting pneumonia. Previous routine antibiotic therapy in these patients was little effective. Administration of the antibiotics into the peripheral lymph nodes provided blocking of the lymphagenic pathway for the infection due to high levels in the lymphatic system. Endolymphatic use of cefuroxime and claforan resulted in a significant improvement of the functions of the T- and B-immunity systems and the indices of natural resistance. The levels of the autoimmune reactions and sensitization to the bacterial antigens decreased. Endolymphatic use of cefuroxime and claforan once every 3 days provided recovery of 9 2.8 per cent of the patients, the treatment periods being decreased 2.5--3 times. Intravenous administration of the drugs according to the routine schemes, endolymphatic use of pentrexyl (5 g once every 3 days) and endolymphatic administration of cefuroxime in a single dose followed by intravenous therapy was less effective. The efficacy of pentrexyl increased, when it was used endolymphatically in combination with lysozyme. Endolymphatic use of claforan in doses of 2--3 g once every 3 days (3--4 infusions during the treatment course) was most effective.

Adult↗