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Biomedical subjects

V N Nikitin

Publications and source records attributed to V N Nikitin.

At least 19 recordsLinked to original sources
PubMed1993

[Dynamics of cell proliferation in rat kidney and effect of endogenous inhibitors].

The age dynamics of albino rat kidney cell proliferation in conditions of compensatory hypertrophy and influence of endogenous inhibitors on this process have been studied. The lack of influence of repeated injection of inhibitors on kidneys cell division of 1-month old rats has been shown, while the level of kidney proliferation of 3-month old rat and 12-month old rat decreased of about 50% and of 24-month old rat decreased of about 34%.

Aging↗
PubMed1989

[A comparative evaluation of the level of sphingomyelinase activity in liver cell nuclei and in the brain].

It was discovered that there is sphingomyelinase activity in the rat liver nuclei. The maximum of enzyme activity is at pH 7.1. The data obtained demonstrated that the main part of sphingomyelinase is located in the nuclear membrane. Comparison of sphingomyelinase activity in cell nuclei, liver and brain homogenates shows high level of enzyme activity in the nuclei. The authors discuss possible participation of sphingomyelinases in changes of phospholipids composition in nuclear structure under different functional activity of cell nuclei.

Animals↗
PubMed1986

[Age-related characteristics of the metabolism of fatty acid components of nuclear phospholipids].

The metabolism of liver nuclear phospholipid acyl components of rats of various age was studied in vitro. It was found that the activity of phospholipases A1 and A2 in the nuclei sharply increased in animals aged 1-3 months, showing a decrease in 12- and 24-month-old animals. The incorporation of labeled arachidonic acid into nuclear phospholipids remained practically unchanged thereby. The age-specific fluctuations in the activity of nuclear phospholipids A1 and A2 may be one of possible reasons of changes in the fatty acid composition of nuclear lipids during ontogenesis.

Aging↗
PubMed1977

[Effect of a periodic growth-retarding diet on changes with age in the hypothalamo-hypophyseo-adrenal system].

Two pacemakers localized in sinoatrial and atrioventricular valves were revealed in the tench heart. In their absence, the ventricular and sometimes the atrial myocardium are capable of initialting the automaticity. Pacemaker's cells of the sinoatrial valve are surrounded by specific area similar to sinoauricular ring in amphibia or sino-caval region in mammals. Characteristics of the action potential in different parts of the tench heart are presented.

Adrenal Cortex↗