Biomedical subjects
Publications and source records attributed to V N Nosov.
The role of statistical methods in the estimation of the toxic effect thresholds upon the ecosystem of chemicals are discussed. The corresponding computational procedures and basic principles are characterized. A simplified statistical method of threshold calculation using the linear regression analysis is given.
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As a result of mathematical simulation a group of signs was formed necessary and sufficient for the description of the oscillatory structure of the cardiac sinus rhythm at the quasi-stationary sections of the recording. The practical employment of the "adjustable" model permits one to obtain the present statistical accuracy of the assessment of signs with a lesser amount of baseline data. A procedure for the automatic measurement of signs by a mini-computer has been elaborated.
To account for the cessation of human life span increase in developed countries, we have studied the Swedish vital statistics over the period of 1901-1978. Approximating age-related mortality dynamics as the sum of the constant (age-independent mortality) and exponential (age-dependent mortality), we have discovered a striking phenomenon consisting in historical stability of age-dependent mortality. It appeared that decrease in total mortality was exclusively due to age-independent mortality which is close now to the limiting (zero) level. The results obtained prove the existence of the biological limit for the average life span and show that the conventional reserves for decrease in mortality have been exhausted. Thus, the problem of life prolongation requires a new way of thinking.
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Application interactive CLASS software for stimulating productive binocular cooperation based on random-dot patterns and stereograms was used for treating strabismus and amblyopia in 105 children during a standard course of treatment. The children were divided into 3 groups treated by the CLASS alone (1), Class + two other application programs (2), and CLASS + traditional methods. General positive changes (improvement of visual acuity, decrease of eye deviation, etc.) were similar in these 3 groups. Positive effect of CLASS exercises on binocular visual mechanisms was significant. Due to precise evaluation of binocular interaction provided by CLASS, positive changes in binocular cooperation and stereovision were attained in 93% of children.