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Biomedical subjects

V N Starosek

Publications and source records attributed to V N Starosek.

At least 19 recordsLinked to original sources

[Estimation of efficacy of the correction methods for hepatic functional disorders in cholestasis of mechanical nature].

Efficacy of the prophylaxis and treatment methods for hepatic insufficiency in obstructive jaundice was studied. The role of an energy-dependent processes and the tissue deficit of oxygen in the hepatic insufficiency occurrence and progress, possibility of these disorders medicinal correction was delineated. The expediency of introduction of preparations, improving the erythrocytes function and the oxygen delivery to tissues in conjunction with miniinvasive biliary decompression, in therapeutic complex for hepatic insufficiency of mechanical nature was noted.

Decompression, Surgical↗

[Versions of the bile outflow restoration in reconstructive and restorative surgery on the bile duct].

The results of performance of 90 restoration and reconstructive operations in 71 patients with iatrogenic injury of extrahepatic biliary ducts were analyzed. The risk factors of iatrogenic injury were delineated. Original methods of restoration of the bile outflow into intestine were offered. The method of external extraperitoneal cholangiostomy via hepatic round ligament was recommended. Total postoperative mortality had constituted 15.7%.

Bile Duct Diseases↗

[Drainage operation for the infectious pancreonecrosis].

The prospective investigation a was conduct in 218 patients and retrospective ones--in 253 patients. The results of drainage operations in infectious forms of pancreonecrosis were studied basic task in preoperative period was adequate antibacterial therapy, directed on all microorganisms.

Anti-Infective Agents↗

[Surgical aspects of treatment of acute pancreatitis and its complication].

The variants of an operative intervention completion were analyzed in 197 patients with purulent-necrotic complications of an acute pancreatitis. There were studied up the advantages and faults of various methods of drainage of purulent-necrotic focus in bursa omentalis and in retroperitoneal space cellular tissue.

Acute Disease↗

[Influence of ozone on biochemical and cytochemical indexes of the blood in early period after experimental hepatic trauma].

The influence of isotonic solution of ozonized chloride sodium (OISCHS) on the peroxide oxidation of lipids (POL) intensity, the antioxidant system (AOS) and aminotranspherase enzymes activity, the middle molecular mass peptides (MMMP) concentration in the blood serum and activity of dehydrogenase in neutrophils of peripheral blood in 1, 3, 6, 9 hours after modelling of mechanical dosaged hepatic trauma was studied in experiment on 20 dogs (principal group). OISCHS was infused intravenously by dropper, the ozone concentration was 1.3-1.5 mg/l. Essential bioregulating effect of ozone brought to the system POL/AOS balance normalization, surveying the aminotranspherases and dehydrogenases, activization, stable lowering of MMMP concentration.

Animals↗

[Choledochotomy and its results].

Of 21 patient to whom after choledochotomy the external drainage of common bile duct was conducted, the suture insufficiency have occurred in 3, 2 patients died. After choledochoduodenostomy conduction the suture insufficiency was observed in 3 of 17 patients, 2 patients died. After papilloshincteroplasty conduction the complications were revealed in 5 of 23 patients, 3 patients died. Of 4 patients, in whom the twin internal drainage was conducted, 3 died.

Choledochostomy↗

[Intralymphatic therapy of peritonitis].

The lymphatic system catheterization methods, the appropriate catheterization side choice were developed by the authors. It was established that the peritonitis progress is accompanied by endolymphatic therapy effect lowering, what demands the application of active organism detoxication methods, hepatoprotective and immunocompensatory therapy.

Anti-Bacterial Agents↗

[Effect of endolymphatic antibiotic therapy on the status of cellular immunity in peritonitis].

The immune status in 68 patients with diffuse and generalized peritonitis was studied. It was established, that a degree of the impairment in immune response depended on peritonitis spreading. Endolymphatic antibiotic therapy had immunostimulating effect in patients with diffuse peritonitis, in generalized peritonitis, this was not observed. In patients with generalized peritonitis, it is necessary to include into the complex of treatment the other methods of immunologic correction.

Adjuvants, Immunologic↗

[Variants of reconstructive and reparative surgery in high strictures and injuries of the biliary system].

The authors' views of the problem of reconstructive and restorative surgery of the biliary tract are set forth and original methods are suggested for external and through drainage after formation of hepatohepatic- and hepaticojejunal-anastomosis (via the inferior surface of the right lobe of the liver in the region of the gallbladder bed and through the round ligament of the liver). Some problems of operative techniques in establishment of the anastomoses are discussed. A total of 39 operations were carried out: 25 reconstructive and 14 restorative. The postoperative mortality was 28.2% (11 patients). Preference is given to restorative operations because they are technically simpler.

Anastomosis, Surgical↗