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Biomedical subjects

V N Tripathi

Publications and source records attributed to V N Tripathi.

At least 19 recordsLinked to original sources

Poliomyelitis with special reference to immunization status.

One hundred ninety one children below 5 years of age suffering from poliomyelitis were analyzed to find out the immunization status and its correlation with the incidence of poliomyelitis. Effects of age, sex, immunization status and seasonal variation on the morbidity and mortality status were studied. The maximum number of cases were admitted during the months of July (23.6%) and August (23.1%). Of 191 cases, 143 (74.9%) had no immunization and 48 (25.1%) were partially immunized. A total of 155 (81.2%) cases had spinal polio, 23 (12.01%) bulbo-spinal polio, and 13 had (6.8%) bulbar polio. Serious illness (bulbospinal and bulbar type) was more in partially immunized children (25%) as compared to unimmunized children (16.8%). The mortality rate was more than two times higher in the partially immunized (29.6%) as compared to unimmunized children (11.2%). The possible explanation for high mortality in partially immunized children could be due to the adverse effect of OPV which has not been studied so far.

Age Factors

Prothrombin time in first week of life with special reference to vitamin K administration.

Prothrombin time was estimated in 100 neonates (80 full term and 20 preterm). Among the full term infants 50 were healthy and 30 sick. Prothrombin time was altered in neonates with birth hypoxia and prematurity (p less than 0.001). Vitamin K administration to anoxic babies resulted in improvement in prothrombin time after 48-72 hours (p less than 0.001). Four newborns has bleeding, 2 had anoxia and 2 were only in preterms who did not receive vitamin K after birth. It is concluded that vitamin K should be given to all preterms and those with difficult deliveries; term, healthy newborns do not need it.

Humans

Blunt renal injury--an experience of 30 cases.

Thirty cases of blunt renal injury are reviewed. The need for rapid and accurate diagnosis of these cases with excretory urography, supplemented in certain patients with renal angiography, is discussed. High-dose excretory urography allows the cases to be categorized into minor or major injuries. All minor injuries can be managed without operation. For major injuries, a conservative approach, if necessary followed by surgical exploration, avoids loss of organ in most of the cases.

Adolescent

Urodiagrams: a new method of uroflow pattern analysis.

Uroflow diagrams, obtained by plotting the mean flow rate at 1-second intervals for controls and patients with bladder outflow obstruction, have been studied in 60 healthy controls and 100 patients. Standard patterns were obtained for male and female controls in 3 different age groups and for patients with various types of lower urinary tract obstruction. Outflow diagrams in age and sex-matched controls were compared to those obtained from patients, indicating the nature and the site of obstruction.

Adolescent

Urethral coitus.

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Adolescent

Urethral diverticulum in male subjects: report of 5 cases.

We present 5 cases of urethral diverticulum in male subjects, of which 2 were congenital and 3 were acquired. Of these diverticula 4 were in the anterior urethra, while 1 was in the posterior urethra. One congenital diverticulum contained multiple calculi.

Adolescent

Muscle involvement in association with filarial chyluria.

Twenty unselected consecutive patients of filarial chyluria were evaluated clinically, electromyographically, and histopathologically for neuromuscular dysfunction. None of the patients showed clinical evidence of muscle wasting or weakness suggesting myopathy, although generalized muscle weakness was complained by all of them particularly while climbing the stairs or on getting up or during lifting heavy weights. Electromyographic abnormalities were found in nine patients and slight histopathological abnormalities in two. The average duration of motor unit potentials and the mean amplitude were reduced, compatible with myopathy. There were no fibrillation potentials. Histological abnormalities consisted of a marked variation in muscle fibre size, sarcolemmal nuclear proliferation, and mild interstitial fatty infiltration. None of the patients showed evidence of clinical neuropathy, abnormalities in conduction velocity along the nerves or signs of segmental demyelination in the biopsy of the nerve. Our data suggest that muscle weakness in these patients is myopathic in nature without peripheral nerve involvement, and is possible due to hypoproteinaemia and hypolipidaemia, as these patients lose excessive amounts of protein and fat in their urine.

Action Potentials

Avulsion injury of uterovaginal prolapse and bladder.

A 40-year-old postmenopausal female with complete uterine prolapse received an avulsion injury when her sari was caught in the fast-moving belt of a flour mill machine. Part of the prolapsed anterior vaginal wall with underlying bladder wall was torn off. Primary repair together with vaginal hysterectomy led to an uneventful recovery.

Accidents, Occupational