Programmed cell death or cell death programme? That is the question.
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Animals↗
Biomedical subjects
V Nasser
Publications and source records attributed to V Nasser.
[Lymphedema and Paget's disease of the scrotum].
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Antineoplastic Combined Chemotherapy Protocols↗
[Molecular typing of breast cancer: transcriptomics and DNA microarrays].
Breast cancer is the most frequent and deadly cancer of women. Its great heterogeneity makes prognosis and response to current treatments highly variable and difficult to predict. Mammary oncogenesis remains poorly understood. These issues should benefit from recent development of techniques capable of large-scale molecular analyses. The use of cDNA array techniques allows for the simultaneous analysis of the mRNA expression levels of thousands of genes in mammary tumor cell lines and breast tumors. Expression profiles will help classify tumors and provide new prognostic tools and potential therapeutic targets. They will also boost our knowledge of the molecular events responsible for the development and progression of this cancer.
Breast Neoplasms↗
Antibodies to endostatin in a multifocal glioblastoma patient.
Endostatin, a C-terminal fragment of collagen XVIII is involved in the regulation of neovascularisation in solid tumours in mice. However, few data are available on the concentration of endostatin protein in patients with cancer. Paradoxical results obtained in this way prompted us to investigate an antibody to endostatin. We detected antibodies to endostatin in the serum and in the tumour brain tissue of a patient with a multifocal glioblastoma, and in the serum samples from two patients with aggressive tumours. These data suggest that endostatin overexpression by tumour tissue might induce a humoral immune response.
Angiogenesis Inhibitors↗