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Biomedical subjects

V P Aggarwal

Publications and source records attributed to V P Aggarwal.

At least 19 recordsLinked to original sources

Clinical and pathological evaluation of large loop diathermy excision of the transformation zone.

In order to make accurate diagnosis and to carry out treatment of cervical preneoplastic disease, large loop diathermy excision of the transformation zone was performed in 98 patients. The colposcopic assessment was indicated by abnormal smear or history of treatment for preneoplastic changes. The entire transformation zone could be excised in one piece in 90% of cases. Histological examination of the specimens confirmed dysplasia in 89% of patients and in 4 cases invasive cervical disease was revealed. The ectocervical and endocervical excision margins were free of dysplastic epithelium in 68% of cases. Compared to traditional cone biopsy, the new method is cheaper and more simple. Loop diathermy excision of the transformation zone can be performed in local anaesthesia as an out-patient procedure and there is no need for postoperative hospitalization. By reducing the number of general anesthesia, the workload in gynaecological theatres and by eliminating the need for postoperative hospital stay the method substantially contributes to the improvement of the hospital budget.

Colposcopy↗

Priapism in sickle cell anaemia: a case report.

Priapism is an unusual and distressing complication of sickle cell anaemia and its management has been varied and generally unsatisfactory. We report priapism in a Libyan boy with sickle cell anaemia, managed successfully by blood transfusion.

Anemia, Sickle Cell↗

The Melkersson-Rosenthal syndrome--a report of two cases.

Melkersson-Rosenthal syndrome (MRS) is a rare condition with variable presentation. In some cases there is sequential development of clinical features. This report describes the syndrome in two Arab children who showed partial response to therapy with oral steroids. Since the natural course of the disease is unpredictable and there may be natural remission of symptoms, the efficacy of steroids is difficult to establish.

Adolescent↗

The pathology in perinatal mortality in Nairobi, Kenya.

The clinico-pathological causes of death in 497 stillbirths and 1st 24 hour neonatal deaths in Nairobi are described. The major factors in stillbirth (303 cases) were cord compression and prolapse, birth trauma, and prolonged labour. Hyaline membrane disease and intraventricular haemorrhage caused death in 52% of the neonatal cases. The importance of intra-uterine infection is discussed.

Bacterial Infections↗