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Biomedical subjects

V P Andriushchenko

Publications and source records attributed to V P Andriushchenko.

At least 19 recordsLinked to original sources

[Diagnostic and prognostic significance of urinary amylase in acute biliary pancreatitis].

The diagnostic significance of amylasuria in the early period of an acute biliary pancreatitis (ABP) course was estimated in 70 patients. High sensitivity of the test during 3 days of the disease course was ascertained as well as a lack of specificity of the criterion concerning differential diagnosis with an acute cholecystitis. The interrelationship between the enzyme activity and lethality was not revealed. It is necessary to take into account the peculiarities of the amylasuria diagnostic-prognostical significance while substantiation of diagnostic program and the treatment tactics for ABP.

Acute Disease↗

[Use of trans-tube treatment program in patients with acute intestinal obstruction and peritonitis].

In 92 patients with enteral insufficiency syndrome, an acute ileus (AI) and diffuse peritonitis (DP) the prolonged small intestine decompression, the small intestine lavage with solution analogous to the chyme by electrolyte composition, medicinal decontamination, enterosorption and intraluminal electrophoresis of medicinal preparations was conducted. The pH magnitude and the degree of microbial contamination were determined; the toxicity in the probe contents according to paramecium test coefficient value was estimated. The advantage of transtube treatment over passive decompression of small bowel was proved, the hospitalization period reduced in AI on average by 7.5 days, for DP--by 11 days, mortality--by 13.2% and 22.5% accordingly.

Acute Disease↗

[The pathomorphological changes in the common bile duct in suppurative cholangitis].

Pathomorphological investigation of suboperative material in 56 patients with purulent cholangitis was conducted to determine the character and peculiarities of the wall structure changes of common biliary duct. In 20 (36%) observations the histological changes were like in acute, and in 36 (64%)--like in chronic inflammation. Comparing the character of changes of the duct wall and the excised gallbladder it was determined that they are unique and presents the morphological substrate of disease. Since histological changes mainly correlate with the malady clinical course it must be taken into account while choosing operative procedure.

Acute Disease↗

[Cholecystectomy using the minimal approach in surgery for calculous cholecystitis].

The experience of cholecystectomy conduction using the small traumatizing access in 16 patients with chronic and an acute noncomplicated calculous cholecystitis was generalized. Method on laparotomy conduction preserving the vascular-nervous branches and the abdominal wall muscles in depicted. Favourable postoperative period course and the lack of complications in patients, the shortening of hospital stay was noted. The authors consider the conduction of such laparotomy procedure in surgical treatment of calculous cholecystitis expedient.

Adult↗

[The use of regional lymphotropic therapy in patients with acute complicated cholecystitis].

The results of the regional lymphotropic therapy application in 58 patients with an acute complicated cholecystitis are presented. The drop-infusion administration of the lymph outflow promoting drugs, antibiotics and antiseptics, proteases inhibitors and cytostatics, immunostimulants was conducted in the postoperative period. The result of the treatment is favourable.

Acute Disease↗

[Programmed relaparotomy in the surgical treatment of acute suppurative peritonitis].

On the basis of the analysis of the use of programmed relaparotomy (PR) in 23 patients with diffused forms of purulent peritonitis, the authors have substantiated the expediency to distinguish the "mandatory" PR (in 15 patients) performed irrespective of the circumstances and the "probably possible" one (in 8), the indications for which are defined at the early postoperative period. In 13 patients the mandatory PR was performed 24-36 hours, in 8-48-72 hours after the first intervention, in 4-two relaparotomies of each type were performed. Postoperative lethality was 35%.

Acute Disease↗

[Prolonged decompression of the small intestine in the surgical treatment of acute intestinal obstruction and peritonitis].

Prolonged decompression of the small intestine was used in the complex surgical treatment of 85 patients with acute ileus (67) and peritonitis (18). The main stage of the operation included liquidation of ileus and elimination of a source of peritonitis. Antegrade nasogastric intubation of the intestine was performed in 54 patients, via gastrostomy--in 3, retrograde intubation via cecostomy--in 15, via appendicostomy--in 4, via ileostomy--in 9. Performance of active transtubal sanation of the intestine by means of antiseptic solutions (53 cases) in combination with enterosorption (17) contributed to essential increase in the effectiveness of treatment.

Acute Disease↗

[The optimal drainage of the bile ducts and subhepatic recess in the surgical treatment of complicated cholecystitis].

On the basis of the analysis of the results of surgical treatment of 478 patients with complicated cholecystitis, it was established that the Robson-Vishnevsky method (95 cases) was the optimal one for drainage of the bile ducts after diagnostic (19) or therapeutic (115) choledochotomy, and that of Halsted-Pikovsky (9)--in manipulations through the cystic duct. Drainage of the subhepatic space by means of a rubber tube drain is effective. The methods for active decompression and transdrain therapeutic measures used in presence of purulent-inflammatory process in the bile ducts, or subhepatic space are presented.

Adult↗

[The principle of staging in the surgical treatment of acute cholangitis].

In 67 patients ranging in age from 47 to 82 years, the transabdominal surgical (35) and instrumental decompressive (32) staged interventions were performed for acute cholangitis. The indications for staged treatment with regard for general factors calculated by means of the mathematical analysis of prognostic criteria, local factors revealed suboperatively and as well their combination are substantiated. It was established that the most effective method of instrumental decompression was endoscopic papillosphincterotomy performed at a specialized medical department. The transabdominal staged interventions can be performed at the in-patient departments of general surgery.

Acute Disease↗

[A diagnostic algorithm in the postcholecystectomy syndrome].

The diagnostic informative value (according to the "sensitivity" and "specificity" tests) of the findings of clinical, laboratory, biochemical (CI, LI, BI), and adjuvant methods of investigation in 74 patients with postcholecystectomy syndrome (PCES), who underwent reoperations, was established. The open to general use diagnostic algorithm of PCES was determined. CI, LI, BI are preliminary screening tests. The use of adjuvant methods, their sequence and combination depend on the character of the diagnostic information obtained.

Adult↗

[Treatment of patients with malignant tumors of organs in the pancreaticobiliary zone complicated by the development of emergency situations].

The results of surgical treatment of patients with cancer of the gallbladder (23), extrahepatic bile ducts (16), pancreas (28), major duodenal papilla (10), with tumour metastases in the liver (10), who developed, as a consequence of the tumour process progression, acute abdominal conditions--inflammatory syndrome, increasing jaundice, high ileus and hemorrhage are analysed. Emergency operative interventions were directed at solving the urgent situations and had, mainly, the palliative character. After the operation, 16 (21%) patients died.

Abdomen, Acute↗