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Biomedical subjects

V P Grishin

Publications and source records attributed to V P Grishin.

7 recordsLinked to original sources
PubMed1992

[The HIV infection processes in a hospital: the prognostic possibilities].

The method of mathematical simulation of the processes of HIV infection in hospitals and clinics is proposed with the aim of predicting the spread of HIV infection throughout the territory of this country. An original mathematical model reproducing, on the whole, the essential properties of HIV infection processes in the course of medical interventions requiring skin punctures has been worked out. An adequate mathematical and computer model imitating the process of HIV infection in a hospital is a convenient instrument for making up prognostic evaluation and for the epidemiological analysis of cases of HIV infection occurring at medical institutions throughout this country.

Carrier State↗
PubMedDate not supplied

[The reciprocal influence of Escherichia coli and Salmonella bacteria in a mixed infection of Ornithodoros papillipes Birula ticks].

The paper presents and analyzes the results of experiments on the Escherichia coli-Salmonella relationships in combined infection of Ornithodoros papillipes ticks. The findings have led to the following conclusions. The body of hungry adult O. papillipes ticks can retain the pathogen of Salmonella infection for a month. This model object is also favourable for avirulent E. coli strain persistent in the body's cavity both alone and in combination with Salmonella typhimurium strain in a 1:1 ratio. Binary carriage in hungry Ornithodoros papillipes ticks revealed that the ticks associated with Salmonella typhimurium and E. coli 083 mcl + lyz No 225, microcine and lysozyme producers, are freed of pathogenic bacteria during 24 hours. The initial bacteria E. coli 083 mcl also suppress salmonellae; however, their elimination occurs much later--in 5 days. Calculating the correlation between the pairs (S. typhi and E. coli) has revealed a linear functional relationship of the rate of E. coli growth to S. typhimurium suppression.

Animals↗
PubMedDate not supplied

[Information-computer modeling of suppression of the infectious tuberculosis process through sterilization of medical instrumentation and equipment by using electrochemically activated aqueous solutions].

The paper deals with the topical problem in the informational computer simulation of suppression of an infectious tuberculosis process by applying electrochemically activated aqueous solutions in order to sterilize medical instruments and equipment. The efficiency of use of electrochemically activated aqueous solutions for sterilization of medical instruments and equipment and for disinfection of other contaminated objects was evaluated by an computer-aided experiment and a retrospective analysis of the epidemic situation by using the original mathematical models of infectious processes by taking into account the aspects of medical engineering technology.

Computer Simulation↗
PubMedDate not supplied

[A dynamic model for analyzing and predicting the epidemic process in typhoid fever].

The results of calculations and theoretical considerations on processes of the spread of typhoid fever, made with the use of a new mathematical model which is based on the model proposed by B. Cvjetanović, further developed and improved. In this new model the latest phenomenology of the description of the processes of the spread of typhoid fever in the heterogeneous susceptible layer of the human population was used. A computer program for the new mathematical model of typhoid fever has been realized on a IBM PC/AT-386, which makes it possible to carry out prognostic analytical studies of the dynamics of the spread of typhoid fever at endemic territories. This program has been used for making calculations in connection with the analysis and prognostication of typhoid fever morbidity and mortality processes in St.-Petersburg.

Convalescence↗
PubMedDate not supplied

[A prognostic model of hepatitis A morbidity].

The growing interest to the study of the processes of the spread of hepatitis A (HA) in big cities of our country has stimulated the development of a new prognostic model at the Gamaleia Research Institute of Epidemiology and Microbiology. The model specifically takes into account a number of factors linked with the dynamics of the development of the disease in 6 stages and some regularities in the seasonal rises of HA morbidity. Quantitative relations in the mathematical model are determined by a system of nonlinear integral-differential equations with the first order partial derivatives and under the integral type boundary conditions, which increases the strictness of modeling of HA. The use of this new model has made it possible to carry out the prognostic-analytical study of HA morbidity among children in Perm and to evaluate a decrease in HA morbidity due to the hypothetical vaccination of children in spring months.

Adult↗