PubMed Health⌕ Search

Biomedical subjects

V P Iatsenko

Publications and source records attributed to V P Iatsenko.

At least 19 recordsLinked to original sources

[Ultrastructure of the ovaries of patients with polycystic ovarian syndrome].

Using electron microscopic techniques, we investigated bioptats of the ovaries of patients with polycystic ovarian syndrome after treatment with clostilbegit, which exerted only insignificant effects. We observed an increases in the intensify of proliferation of the connective tissue elements in the ovaries with the involvement of immunopathological processes against the background of tissue and circulatory hypoxia.

Clomiphene↗

[Tropaphen in experimental drug therapy of cor pulmonale].

The influence of alpha-adrenoblocking drug tropaphen on cardio- and haemodynamics under experimental lung-heart failure was studied in dogs. The findings suggest effectiveness of tropaphen administration in such pathology shown by a decrease of lung hypertension and heart overload, significant increase of the contractile activity and relaxation properties of myocardium of both ventricles and in cardiac pump function optimization.

Adrenergic alpha-Antagonists↗

[The blood microcirculatory bed of the tunica muscularis of the human esophagus in postnatal ontogeny].

The analysis of morphological and morphometrical data of the muscular membrane and its blood microcirculatory bed has demonstrated that their development during the postnatal ontogenesis advances unevenly. An intensified growth and development of the muscular membrane morphological structures, including its blood microcirculatory bed occurs from 3 up to 30 years of life. Their maximal growth is noted from 12 up to 30 years of age. The stages of intensified development of the muscular membrane and its blood microcirculatory bed change into stages of retarded growth, where processes of involutive character preponderate. This is especially noticeable from 60 and more years of age. The stages noticed in the muscular membrane development and its blood microcirculatory bed are characterized both by general and topographical morphofunctional peculiarities specific for every stage of organogenesis.

Adolescent↗

[Morphometric study of skeletal muscle of Gallus domesticus denervated during the early stages of ontogeny].

The musculus soleus has been studied in 19-day-old embryos, 4-day-old and 10-day old independently hatched chickens, that are subjected to a complete dissection of their sciatic nerve on the 18th day of development. Dynamics of changes in the muscle fiber diameter (MFD) are statistically evaluated in control animals and also in the operated muscle (OM) and in the contralateral (CL) extremity of the experimental animals. In the OM, the MFD is changing step-by-step, decreasing noticeably by the end of the observations. This demonstrates an increasing atrophy of the muscle fibers (MF). In the CL of 1- and 4-day-old chickens the MF hypertrophy is revealed, the latter is connected with a natural physical loading on the CL during hatching. As demonstrated the results on dynamic changes of statistic moments of higher order (asymmetry and excess), as well as comparison ranges of the MF distribution classes participating in atrophy and hypertrophy processes, it is possible to conclude that by hatching in the muscles studied various MF groups are forming, they differ in their level of differentiation and functional properties. Taking into account the literature data, a conclusion is made that functional stabilization of the MF at the final stages of their differentiation and appearance during this period of ontogenesis certain compensatory reactions--an ability of the embryonal muscles to be subjected to hypertrophy in response to an increased loading--is performed with participation of some central regulatory mechanisms that have maturated by that time.

Adaptation, Physiological↗

[Quantitative study of aortic wall permeability].

Fluorescent microscopy with trypan blue was used to assay aortal wall permeability. The dye permeation to the vascular wall was assayed by photometry with graphic data recording. The technique described enabled exploring aortal wall permeability in rabbits with experimental hypertension associated with induced atherosclerosis.

Animals↗

[Comparative evaluation of biodestruction of polyurethanes synthetized on the basis of simple and complex polyesters].

In model liquids and experimental animals (rats, rabbits) with the aid of physico-mechanical and histological methods (using interferentially polarizating microscopy) a comparative evaluation was made of the biodestruction of polyurethanes from synthetized simple and complex polyesters. The tissue reaction to intra-abdominal, intramuscular and subcutaneous implantation of perforated stripes of A-19 and Nr. 36 polymer was moderate. Two weeks post-operative increased volumetric biodestruction of the polymers was observed. The course was different in various standards and depended upon the chemical structure of the polymers. Taking into account the slight macrophage tissue reaction, in counterdistinction to the significant volumetric biodestruction which envolved the entire width of the polymer strip, it is assumed that the destruction of the investigated polyurethane composition (adhesive KL-3) takes place by hydrolysis 3 to 6 months post-implant.

Animals↗

[Density of receptor neuron nuclear membrane pores during the early ontogenesis of Gallus domesticus L].

In 10, 14, and 18-day-old embryos, as well as in 3, 14 and 30-day-old chickens, neurons of cerebrospinal ganglia have been studied electron microscopically. A method for quantitative evaluation of pores in nuclear envelope by means of estimating pore density index (PDI) has been suggested. By methods of regressive analysis it has been stated that neuronal development and differentiation in the cerebrospinal ganglion at embryonal and early postnatal ontogenesis of Gallus domesticus are accompanied by a regular increase in density of pores per stipulated unit of the nuclear envelope area. During the studied period of the hen ontogenesis, PDI has a characteristic exponential dependance. A suggestion is made to use the index of the pore density as a criterion for estimating functional state of the receptor neuron.

Age Factors↗

[Role of macrophages and foreign body type giant cells in the biodestruction process of polyurethane adhesive tissue].

The biodestruction process of polyurethane adhesive was investigated in application to intestine anastomoses, wounds of skeletal muscles and surfaces of some internal organs. The polymer destruction was proved to be connected with the activity of giant cells of foreign body type and macrophages phagocyting the micromolecules of the adhesive. The presence of adhesive microfragments in macrophages and giant cells was ascertained on the basis of a method elaborated by the authors consisting in staining of the polyurethane adhesive with Sudan III-IV. Moreover, it was pointed out, that biodestruction products had no negative effect in the regeneration of nervous and muscle fibers.

Animals↗