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Biomedical subjects

V P Kaznacheev

Publications and source records attributed to V P Kaznacheev.

At least 19 recordsLinked to original sources
PubMed1979

[Conditions controlling the development of distant intercellular interactions during ultraviolet radiation].

The study is concerned with ascertaining the role of UV radiation in distant intercellular interactions (DII) and the conditions resulting in "MIRROR" CYTOPATHIC EFFECT ("M" CPE). It has been found that the UV radiation-induced extreme state of the cells in a radiant culture produces distantly in an intact detector culture, which has only an optic contact with it, the cytopathic effect (CPE) as a repercussion of a specificity of morphological manifestations imprinted in the affected culture. UV preparadiation of the detector cells aids in manifestation of the "mirror" CPE.

Adenoviruses, Human↗
PubMed1978

[Effect of several hormones on the intensity of experimental free-radical lipid oxidation reactions].

The effect of adrenaline and hydrocortisone on the processes of free radical oxidation of lipids in rabbit erythrocytes was studied in experiment in vivo against the background of altered lipid metabolism. Adrenaline in a dose of 0.1 mg/kg and hydrocortisone in a dose of 5 mg/kg induced an increase in the amount of hydroperoxidase of fatty acids recorded by the changes of the UV spectrum. The data obtained served in confirmation of the fact that adrenaline and hydrocortisone possessed prooxidant properties, apparently mediated, this being connected with their fat mobilizing effects.

Animals↗
PubMed1978

[Diurnal variations in the cellular composition of peripheral blood in mice of different genotypes].

Changes of the circadian rhythm of the general numbers of nucleus-containing cells and leucograms of peripheral blood in NZB mice with autoimmune spontaneous hemolytic anemia and in C57BL mice without visible disturbances in the system of immunostructural homeostasis were the most obvious in the white blood in NZB mice: a) disappearance of the circadian rhythm of the general number of nucleus-containing cells in peripheral blood owing to the inversion of circadian rhythm of the absolute number of neutrophiles; b) changes of circadian fluctuations of lymphocytes-neutrophiles ratio. The observed differences in circadian rhythms of hematological indices in NZB and C57BL mice seem to stem from insufficiency of adrenal cortex function and/or changes in functional state of hemopoietic tissue which can occur during the development of autoimmune processes.

Anemia, Hemolytic, Autoimmune↗
PubMed1977

[Effect of UV-irradiation on human serum under normal and pathologic conditions].

The influence of the wide UV-spectrum on the level of dien conjugations in the blood serum of donors and patients with various pathological processes was studied. The level of dien conjugations increased statistically significantly in the lipid sera of donors after UV-irradiation; but it proved to decrease in the patients with inflammatory diseases. As to the patients with benign and malignant tumours, UV-irradiation showed practically no influence on the dien conjugation level in the blood serum lipids. This method can be used to elaborate the differential-diagnostic criteria of diseases of tumour and inflammatory nature.

Blood↗
PubMed1977

[Study of a trophoblast cell culture in vitro].

The authors obtained trophoblast culture from an early chorion of human embryo. Trophoblastic cells of the main 4 types described were: giant cells, with processes, fibro-blast-like, and round. All the cells were rich in RNA, glycoproteins, had a set of enzymes of the Krebs pentose cycle, but low activity of succinic dehydrogenase. A marked cytooxic effect of lymphocytes from healthy pregnant woman on the allogenous cells of the trophoblast culature and the absence of any interaction between the neoatal lymphocytes with the latter was revealed.

Cells, Cultured↗
PubMed1976

[Phenomenon of human peripheral blood lymphocyte interaction with autologous erythrocytes].

Phenomenon of the lymphocyte interaction with autologous erythrocytes was revealed in the patients with auto-immune diseases. Macroscopically this phenomenon appeared in the form of hemagglutination, and microscopically--of "rosette" formation. No lymphocyte interaction with autologous erythrocytes was found in the group of normal subjects and patients without autoimmune disorders.

Adult↗