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Biomedical subjects

V P Mashilov

Publications and source records attributed to V P Mashilov.

At least 19 recordsLinked to original sources
PubMed1996

[Complications of food poisoning and salmonellosis].

During the follow-up of 32,448 patients with food poisoning and salmonellosis complications occurred in 665 (2.01%). Among them were general circulation disorders (shock), myocardial infarction, acute cerebral vascular accidents, mesenterial thromboembolism, pneumonia, acute renal failure (0.09, 0.4, 0.4, 0.1, 0.5 and 0.6% of patients, respectively). Complications of food poisoning and salmonellosis caused lethal outcomes in 0.03% of cases. For the last 15 years acute adrenal insufficiency in patients with food poisoning and salmonellosis has not been reported.

Foodborne Diseases↗
PubMed1996

[The clinical manifestations and treatment of shock in acute intestinal infections].

Shock (hypovolemic and infectious-toxic) is a severe complication of acute intestinal infections. Of 35096 patients with acute intestinal infections (90.6% had food poisoning, 9.4% had salmonellosis), 24 (0.07%) patients developed hypovolemic, 26 (0.08%) infectious-toxic shock. Hypovolemic shock is based on decompensated dehydration, infectious-toxic one arises from generalized circulation disorders with severe affection of hemostasis. Hypovolemic shock was effectively managed with polyionic crystalloid solutions. In infectious-toxic shock hemodynamic and homeostatic defects should be corrected. In spite of intensive therapy, lethality in infectious-toxic shock in patients with acute intestinal infections reached 80.8%.

Acute Disease↗
PubMed1996

[The treatment of patients with intestinal infections at a polyclinic].

It is thought possible to provide for the patients all the necessary therapeutic measures (detoxication, rehydration, recovery of intestinal function and its microbiocenosis) against mild and moderate acute intestinal infection at home. Etiotropic chemotherapy needs special indications.

Acute Disease↗
PubMed1995

[Acute intestinal infections and chronic alcoholism].

153 chronic alcoholics were given treatment against food poisoning. 55 of them developed withdrawal syndrome, 98 had alcoholic psychosis including 88 with delirium tremens. The acute intestinal infection in these alcoholics was managed with rehydration using polyionic crystalloid solutions under controlled diuresis. Previous relief of central excitation contributed much to a positive treatment outcome.

Acute Disease↗
PubMed1994

[The differential diagnosis of anthrax in man].

The paper reports group cases of the disease running as anthrax. The disease was not identified etiologically. The authors hold that it is important to make differential diagnosis of anthrax with necrobacillosis, pasteurellosis and contact pustular viral dermatitis. Laboratory and clinical diagnostic techniques are specified.

Adult↗
PubMed1993

[Acute kidney failure as a complication of food poisonings].

Literature data and original experience are reviewed on the treatment of alimentary toxoinfections complicated with acute renal failure (ARF). Out of 192 patients prerenal ARF was recorded in 74.5%, renal in 25.5% of the cases. ARF resulted from hemodynamic disturbances, salt and water loss, intoxication. ARF clinical symptoms were poor, the patients developed decompensated metabolic acidosis and hyperazotemia. Pathological and histological evidence is available for 17 patients with "shock kidney". They died of infective toxic shock. The treatment of ARF complicating acute alimentary toxoinfections in 98.9% made a success if implied polyion crystalloid solutions. Hemodialysis was demanded in 1.1% of the cases.

Acute Kidney Injury↗
PubMed1990

[Clinical characteristics of the outbreak of Salmonella infection caused by Salmonella enteritidis].

The data are presented on an outbreak of salmonellosis induced by S. enteritidis. Gastrointestinal symptoms were recorded in 97.8% of 90 patients, 2.2% of them developed a generalized form. The disease ran a moderate course in 84.5% and a severe course in 2.2% of the patients majority of whom suffered from intoxication and dehydration. The therapeutic response was achieved upon rehydration treatment with crystalloid solutions.

Adult↗
PubMed1990

[Errors in performing pathogenetic therapy in acute intestinal infections].

The authors describe the data obtained by them during many years of pathogenetic treatment of patients with acute intestinal infections. Note the main errors made during treatment and giving rise to unfavourable outcomes. Give practical recommendations for carrying out pathogenetic therapy bearing in mind the age-associated characteristics and associated diseases. Draw the clinicians' attention to infusion therapy.

Acute Disease↗
PubMed1990

[Experience in using new drug preparations for treating adult patients with acute intestinal infections].

Ciprofloxacin (Bayer, FRG), a derivative of hydroxyquinolone acid, was used for the treatment of patients with shigellosis and salmonellosis and for the sanitation of Salmonella carriers. The drug turned out to exert a positive effect on bacteriological sanitation of the body. In order to treat patients with food toxinfection of unknown etiology, use was made of intetrix (Farmacos, Socialist Federal Republic of Yugoslavia). Inclusion of the drug into combined treatment of patients with food toxinfections did not show any material advantages.

Acute Disease↗
PubMed1989

[Pancreatic hormones and gastrin in patients with acute dysentery].

The incretory pancreatic function has been studied in 35 patients with a moderately severe course of acute dysentery. The blood plasma content of insulin, glucagon and gastrin was determined by means of radioimmunoassay with standard kits during the acute course of the disease and prior to discharge of patients. The endocrine pancreatic function was found to be deranged with an increased insulin content during convalescence; the glucagon content was decreased during the period of the disease and the gastrin content was decreased in the acute period.

Acute Disease↗
PubMed1988

[The importance of secondary immune deficiencies in the pathogenesis of dysentery].

Some immunity indices were studied in patients with acute dysentery. The number of total and active T-lymphocytes, T mu- and T gamma-cells, T-rabbit, T-staphylococcal, B-total and B-lymphocytes forming rosettes with mouse erythrocytes were determined for assessment of the immune status. Changes in the above indices with relation to the severity of the disease were noted. Suppression of the T- and B-systems of immunity were noticeable in patients with a severe and lingering course of disease. Delayed time of complete convalescence was observed in patients with a marked imbalance of indices of the T- and B-systems of immunity during convalescence.

Acute Disease↗
PubMed1988

[Indices of endocrine activities of the digestive organs in patients with dysentery].

Some indices of pancreatic endocrine function were studied over time in patients with acute dysentery. The plasma levels of insulin, C-peptide, glucagon, and gastrin were determined by a radioimmunoassay. 35 patients and 30 healthy controls were examined. Clinical signs of the affection of the pancreas in the patients were undetectable. However, significant reduction of the level of C-peptide in the acute period of disease as compared to the normal level, an increase in the level of insulin during early convalescence, and the reduction of gastrin concentration during the entire period of disease were noted. These indices are indicative of disorder of pancreatic endocrine function in patients with acute dysentery.

Acute Disease↗