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Biomedical subjects

V P Molodtsova

Publications and source records attributed to V P Molodtsova.

16 recordsLinked to original sources

[Effect of halogen aerosol therapy on resistance parameters of the respiratory tract].

AIM: Assessment of the efficacy of dry high-dispersive aerosol of sodium chloride--the main acting factor of haloaerosol therapy--on defense system of the respiratory tract. MATERIAL AND METHODS: 188 patients with respiratory disease and at risk of pulmonary pathology received course of haloaerosol therapy. 49 matched patients were given placebo. The effect of the treatment was assessed by clinicoendoscopic picture, cytomorphological and bacteriological characteristics of the bronchoalveolar lavage, contamination activity of the microflora, activity of local humoral immunity in pharyngeal brush-biopsies and saliva, rheological indices of the sputum. RESULTS: Dry aerosol of sodium chloride demonstrated antiinflammatory activity in the respiratory tract, mucoregulating action. It enhances drainage of the bronchi, activates alveolar macrophages, improves biocenosis and local humoral immunity. CONCLUSION: Haloaerosol therapy has positive effect on the defense system, improves function of the respiratory tracts.

Administration, Inhalation↗

[Laryngobronchofibroscopy in the diagnosis and treatment of acute purulent mediastinitis].

Laryngopharynx and tracheobronchial tree were examined in 20 patients with purulent mediastinitis (PM) of different origin. Endoscopically, upper posterior mediastinitis was characterized by swallowing of membraneous wall into the lumen due to pressure outside. The authors recommend diagnostic application of laryngobronchofibroscopy to verify PM following traumas of the respiratory tracts and therapeutic use of the above procedure to treat PM complications; propose to perform nasotracheal intubation using bronchofibroscope as a method of choice in prevention of asphyxia in PM patients provoked by laryngeal edema.

Adult↗

[Immunoreactivity in acute bronchitis].

In 20 patients with acute bronchitis (AB) the results of the investigations of cellular and humoral immunity and the phagocytic system were compared with a clinical and bronchoscopic picture of disease. The acute period of disease was characterized by considerable activation of the majority of immunoreactivity indices. Complete normalization of the immune status and clinical findings was observed only 3-4 mos after recovery.

Acute Disease↗