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Biomedical subjects

V P Sen'ko

Publications and source records attributed to V P Sen'ko.

At least 19 recordsLinked to original sources

[Immunologic effect of hemosorption in patients with acute peritonitis].

An examination of 65 patients with acute diffuse peritonitis has shown that pronounced T-immune deficiency is observed in the postoperative period of acute peritonitis. Hemosorption was shown to be efficient in patients with high content of toxin which allows considering the method of extracorporeal detoxication as effective means of immune-correcting therapy in peritonitis patients with high level of toxinemia who make up a group of risk.

Acute Disease↗

[Adaptation reactions in acute peritonitis and their correction using sorption detoxification].

Examined were 233 patients with acute peritonitis. In patients, who underwent the conventional intensive infusion therapy alone, in complicated course of the postoperative period, within 28 days, the high level of pathologic stress reactions was observed, which correlated with changes in the content of middle molecular mass peptides (MMMP). In uncomplicated course of the postoperative period, the MMMP level and adaptation reactions didn't differ from the control findings. Hemosorption in patients with high toxin level was accompanied by the decline in MMMP concentration below the diagnostic level, restoration of physiologic adaptation reactions.

Acute Disease↗

[Effect of hemosorption on the level of medium molecular mass polypeptides and humoral immunity in patients with peritonitis].

An examination of 43 patients with acute diffuse peritonitis of various etiology has revealed different direction of the dynamics of indices of humoral immunity (M, G, A immunoglobulins, general complement activity, circulating immune complexes) depending on the level of middle mass polypeptides (MMP) in the patient's blood. Hemosorption in peritonitis was established to allow rapid and effective elimination of MMP in patients with high content and thus control critical endotoxicosis.

Acute Disease↗

[Malignant tumors of the gallbladder].

On the basis of their personal experience (43 observations) the authors are discussing problems of the preoperative and intraoperative diagnosis, immediate and remote results of the surgical treatment of carcinoma of the gallbladder. Early cholecystectomies in patients with "gallbladder block" and in patients with a long-standing acalculous cholecystitis are considered to be a prophylactic measure. The importance of oncological suspicion and dynamic dispensary observation of patients with chronic cholecystitis is emphasized.

Adenocarcinoma↗