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Biomedical subjects

V Păunescu

Publications and source records attributed to V Păunescu.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[Risk factors for the immediate outcome of gastrointestinal bleeding in patients with cirrhosis].

The risk factors in the immediate outcome of gastrointestinal bleeding were examined in a prospective study of 134 patients with liver cirrhosis. The hemorrhagic episode has a negative prognosis in the immediate outcome (p < 0.01), recording 48 (35.82%) deaths. The deaths occurred in the acute phase of bleeding (n = 18; 13.40%), after recurrent hemorrhage (n = 24; 17.23%) and in 6 other cases (4.47%) after sclerotherapy or surgical treatment of varicosities. After varicose veins sclerotherapy (n = 8), 2 deaths were recorded and 4 other after surgery (n = 22). The advanced stage of cirrhosis, Child C stage, (n = 62) was accompanied by most of deaths (n = 38; 61.29%) (p < 0.01). Among the risk factors responsible for death, there were recorded: encephalopathy (p < 0.05), jaundice (p < 0.01), altered general status ((p < 0.01) and increased seric level of bilirubin over 3 mg% (p < 0.001). Jaundice is among the risk factors with the highest sensitivity (83.33%) and seric bilirubin over 3 mg% has the highest positive predictive value (64.28%).

Aged↗
PubMedDate not supplied

[Predictive value of diagnostic tests in polytrauma patients with abdominal and craniocerebral injuries].

In a study on 1024 polytrauma patients with craniocerebral injury, abdominal injury was present in 206 (20.11%) of them. In order to identify the intraabdominal organs injury, physical examination and specific diagnostic tests will be used. Their value was calculated by means of informational indices. The main indices, sensitivity, positive predictive value and accuracy were: for physical examination = 81.06%, 90.3%, 94.72%; for peritoneal lavage = 94.17%, 95.12%, 97.94%; for abdominal computed tomography = 98.44%, 97.65% and 99.25%. As one might expect the abdominal computed tomography is the most accurate method for the diagnosis of intraabdominal organs injuries.

Abdominal Injuries↗
PubMedDate not supplied

Factors of prediction of immediate postoperative evolution in cancer of the colon.

A study carried out in 152 patients operated on for cancer of the colon showed that the early postoperative evolution of disease depends on the therapeutic method chosen according to the clinical stage of the tumor. The 31 deaths recorded in the first 30 postoperative days occurred mostly in the first week (45.1%) and were due either to hydro-electrolytic disturbances (69%) or to intraperitoneal septic complications (65%) with 0.66 and respectively 0.60 positive predictive value. Advanced forms of disease, emergency surgeries and presence of associated diseases are statistically significant risk factors.

Age Factors↗
PubMedDate not supplied

Influence of age on the surgical treatment of cancer of the colon.

The study of 152 patients with cancer of the colon (CC) showed that age represents a factor of risk in the evolution of disease having a decisive influence on the immediate and delayed results of the surgical treatment. Over two thirds of the cases with advanced clinical stages were detected in subjects over the age of 50. In young agers the evolution of CC was severe and metastases appeared early. In old agers the incidence of disease increased and postoperative mortality was maximum. The mean postoperative survival time in the extreme age groups (young and old agers) was short in all the clinical stages.

Age Factors↗
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Immediate and delayed results in complicated cancer of the colon.

In 34 patients operated on in emergency for complications of cancer of the colon (CC) it was found that complications prevailed in stage III of disease and were mainly represented by occlusions which were more frequent in left colon cancer. Radical surgery proved preferable to the palliative one. The mean survival time in months after emergency surgery for complications of CC was longer for right colon localizations and after radical surgery. The survival after 5 years was of 13%.

Colectomy↗
PubMedDate not supplied

Immediate and late results in the surgical treatment of gastric cancer.

The study of 248 patients mostly males, aged over 50 years, operated on for gastric cancer (GC) has shown that the majority were in stages III and IV of disease. The antral localization of the tumor was the most frequent. In 6.45% of the cases acute complications occurred during the evolution of gastric cancer. Association with other diseases was found in proportion of 5.64%. The surgical treatment was differentiated according to the site and evolutive stage of the tumor but the most frequent was radical subtotal gastrectomy. The postoperative complications were either general or local. Postoperative mortality was higher in cancers situated in the upper third of the stomach, after total gastrectomy, and in stage IV of disease. The 5-year survival was 66.66% for stage II and 10.18% for stage III and the 10-year survival decreased to 40 and respectively 1.85%.

Adenocarcinoma↗
PubMedDate not supplied

Factors predicting postoperative morbidity in biliary calculi.

Statistical analysis of a group of 1,114 patients operated for biliary lithiasis shows that the gravity of the disease, the nature of the complications that accompany it, the need to approach the common bile ducts (CBD) and age, stand at the origin of postoperative complications. To reduce postoperative morbidity elective surgery should be performed in cases of biliary lithiasis with paucity of symptoms during periods free of an attack and before the patient ages.

Aged↗