Chromophobe renal cell carcinoma in pregnancy: case report and review of the literature.
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Biomedical subjects
Publications and source records attributed to V Palmara.
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The Authors analysed from an anatomo-clinical point of view, 17 cases of ovarian fibroma, observed during the period between 1968 and 1992. The incidence of ovarian fibroma in this study was 2.52% and it affected women in different age groups, though with greater frequency those above 50 years. Even the symptomatology was variable and was characterized by pain in the hypogastric quadrant (47.1%); alteration of the menstrual cycle (17.6%); metrorrhagic episodes (17.6%); sterility (5.9%). Due to the fact that the ovarian fibroma can appear at any age, this suggests different surgical approaches according to age, general conditions of the patient and fertility.
It has been amply demonstrated that uterine leiomyoma possess estrogen receptors. On the basis of this presupposition, it is considered logical to use GnRH-agonists which, by reducing the level of estrogen, also reduce the volume of the leiomyoma, although to a varying extent. The maximum reduction which can be obtained occurs, according to published data, between 3 and 6 months of treatment, attaining mean values of approximately 50%. In the author's experience the treatment period was shortened even further by administering only 2 vials of leuprolide depot each month to women who subsequently underwent hysterectomy. The sample group comprised 30 women with uterine leiomyomatosis, of whom 15 were treated with a GnRH analogue and 15 with placebo. The reduction of uterine volume was evaluated by echography and was found to be 40% in the treated group, whereas non change was detected in the "placebo-group".
After reviewing the literature on this topic, the paper examines fetal effects during maternal anti-hypertensive treatment, assessing both possible teratogenic results and fetal outcome. All anti-hypertensive agents cross the placental barrier and are present in varying concentrations in the fetal circulation, thus provoking varying effects on the cardiocirculatory apparatus and fetal metabolism. Some agents, such as alpha-metildopa, may be considered reliable, whereas others, like ACE-inhibitors, are still used with considerable caution, an attitude which will only change following extensive clinical trials and through post-natal checks.
We report on our initial experience with laparoscopically-assisted vaginal hysterectomy. Seven patients aged 41 to 67 years were successfully treated with this new technique without significant morbidity and with the advantage of early discharge and return to full activity. We discuss the indications, technical details including preparation and positioning, and the shortcomings and problems encountered. It is concluded that laparoscopically-assisted vaginal hysterectomy may in the near future become a valid alternative to the conventional procedures in selected cases.
Morphometric reliefs on the enamel of the lower incisor of albino rats in correspondence with the prism compaction area during the first third of the ameloblastic modulation phase have been carried out. The reliefs were done on the longitudinal and median fracture plane and on the transversal fracture plane 8 mm from the cervical ansa. Measurements of the diameters of the honeycomb pits were carried out during the deposition phase, following removal of the ameloblastic coat. The data obtained were fed into an Apple Macintosh 512K/800 computer to obtain the geometric reconstruction of an isolated prism, the relations between each portion of the prism and the respective pits and a graphic example of the architectural organization of the enamel. It was shown that each prism consists of three distinct portion, just as there are three types of honeycomb pit. The external orifice of each pit is complementary to the interdigitant portion of the Tomes process, so the study of the pits may be used to evaluate the spatial orientation of the rods and not the morphology of their section. Cross-over between rows of contiguous rods occurs throughout the thickness of the internal enamel layer. The enamel possesses a particularly suitable structure for the transformation of surface type tangential forces into stresses or prevalently compression type.
Pregnancies after repeated cesarean sections are often considered to carry high maternal and fetal risks. The pregnancy course, intraoperative and postoperative complications and conditions of newborns were compared between 53 patients who had two or more previous cesarean sections and 58 women sectioned for the second time. No statistical difference was found between the two groups except for intraoperative complications.