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Biomedical subjects

V Paskaleva

Publications and source records attributed to V Paskaleva.

13 recordsLinked to original sources
PubMed2005

[Mesenteric venous trombosis and pregnancy--a case report and a short review of the problem].

Mesenteric venous thrombosis is extremely rare surgical pathology during pregnancy and frequently is associated with hemoglobinopathies beta-thalassemia, congenital defects of the coagulation and antiphospholipide syndrome. It has nontypical clinical appearance, which hardens the timely diagnosis and the adequate surgical treatment. We present a case of a 22 year-old girl with hemozygote form of beta thalassemia, pregnant in ml II, with mesenteric venose thrombosis. The diagnosis was made on the 24th hour from the beginning of the disease. The patient was operated successfully by a resection of the necrotic changed part of the intestine. She noticed vaginal bleeding due to a missed abortion on the 22nd day after the operation.

Adult↗
PubMed2004

[Oxidative stress in preeclampsia].

Preeclampsia is the main case of maternal and perinatal mortality. In women with preeclampsia antioxidant activity of plasma is decreased. Increased levels of lipid peroxidation products may case peroxidative damage of vascular endotelium and result in clinical symptoms of preeclampsia.

Antioxidants↗
PubMed2004

[Oxidative stress in preeclampsia].

Preeclampsia is the main case of maternal and perinatal mortality. In women with preeclampsia antioxidant activity of plasma is decreased. Increased levels of of lipid peroxidation products may case peroxidative damage of vascular endotelium and result in clinical symptoms of preeclampsia.

Antioxidants↗
PubMed2004

[Treatment of iron-deficiency anaemia with ferrous gluconate].

Twenty women with iron-deficiency anaemia were treated. The distribution of women was as follow: 16 women with metrorrhagia and 4 pregnant women. According the stage of anaemia - 6 of them with slight anaemia, 12 - moderate, 2 of them with severe anaemia. Diagnosis of iron-deficiency anaemia was done on the base of clinical and laboratory dates, including Hb, Er, Fe and Fe-binding capacity measured in periphery blood. "Tot'hema" was prescribed twice daily. Control laboratory investigations were done on 24 and 72 hours. Receiving dates confirmed excellent GI absorption, which guarantee "Tot'tema" efficacy. Reported on all cases very good therapeutic effect and excellent tolerability of "Tot'tema", without side effects.

Adult↗
PubMed2002

[Drug treatment of tubal pregnancy with methotrexate, with an analysis of 5 cases].

The authors present 5 cases of ectopic pregnancy, treated successfully with Methotrexate. Followed are the levels of beta-fraction of human chorionic gonadotropin. Later on, in two of the patients developed intrauterine pregnancy, which terminated successfully with the delivery of healthy term infants.

Abortifacient Agents, Nonsteroidal↗
PubMed2000

[The use of prostaglandins in atonic uterine hemorrhages following vaginal delivery].

The authors examine the results of usage of Prostin 15M (Upjohn) in series of 19 women with hypotonic uterine bleeding after vaginal delivery. For the same period (1997) 1179 deliveries were performed in the Department of Obstetrics and Gynecology in HMS-Plovdiv. Positive effect was noted in 16 of the cases (84.22%). Unsatisfactory effect was marked in 3 of the cases--15.78%. Three of the women demonstrated adverse reactions after application of Prostin 15M.

Adult↗
PubMed2000

[Overuse of cooking salt by pregnant women in Bulgaria].

The authors investigate the ovemse of salt by pregnant women in two aspects--as a detrimental nutritive habit and as a factor in the pathogenesis of hypertensive disorders during pregnancy. The study involves 140 pregnant women who were given a specially designed questionnaire in order to examine their nutritional habits. One third (33%) of them intake additional amount of salt during nutrition. Almost half of them (43%) add salt before tasting the meal. This is exclusively seen in the group of women above 30. Additional 2-3 grams of salt are intaken while eating salty cheese and pickles during the winter. The approximate amounts of salt for each trimester of pregnancy are calculated. The authors defined which foods are the greatest contributors of salt and make the conclusions of the detrimental impact of overuse of salt during pregnancy on the mother and the child.

Adult↗
PubMed1999

Prostaglandin E2 in preinduction cervical ripening in postdate pregnancy.

UNLABELLED: Unripe cervix is a widely recognised factor contributing to the failure to induce labour. Its presence is associated with high frequency of operative delivery, adverse fetal outcome and high maternal morbidity. MATERIAL: We studied the efficacy of PGE2 application for preinduction cervical ripening in women with postdate pregnancy. Two PGE2-containing preparations were used--Prepidil-gel and Prostin E2 (Upjohn). They were administered to 42 women with postdate pregnancy, unripe cervices and indications for labour induction. The study sample was divided into two groups: group I (20 women) received Prepidil-gel, group II (22 women)--Prostin E2. RESULTS: 85.7% of the women responded favourably to the ripening effect of PGE2. There was no difference in the efficacy, safety and outcome of pregnancy between the two groups. CONCLUSION: Prostaglandin PGE2 is effective for preinduction cervical ripening in women with postdated pregnancy. The authors give their preference to Prostin E2 because it is easier to apply.

Administration, Intravaginal↗
PubMed1998

[The choice of the uterine-contraction agent in managing the placental period of labor based on our data].

Every obstetrician is acquainted with the existing risk during the placental stage. The danger of a greater blood loss is always present. The use of uterotonic medicines reduces the post-delivery bleeding. The authors have carried out observations over 422 delivery cases. In 153 of them ergotamine has been applied in the placental stage, in 121 oxytocine, and in 148 delivery cases the placental stage has passed without uterotonic drugs. The authors have concluded that the application of contracting medicines reduces the blood loss, but their usage has to be selective and after delivery of the fore shoulder of the foetus.

Adult↗
PubMed1997

[The characteristics of labor in multifetal pregnancy based on our data].

The pregnancy and delivery in multifetal pregnancy most often are accompanied by complications and by a high degree of risk both for the mother and the foetus. The successful and of the delivery depends on the condition of the mother, the good obstetric status, the gestation age of the foetuses and their presentation. The authors have followed the characteristic of the delivery in multifetal pregnancy over 10-years material in 137 cases of pregnancy. After strict indications, in 26 cases the delivery has been completed though caesarean section. In 111 cases the delivery has been vaginal. A characteristic of the delivery has been made and it has been expressed in diagrams. The authors have been successful in the vaginal deliveries in multifetal pregnancy. They emphasize the active observation of the patient, especially in the first stage, and the monitoring of the foetus.

Bulgaria↗
PubMed1996

[A procedure for delivery in multiple pregnancy based on our data].

The multifoetal pregnancy has not lost its significance both in terms of its course and its method of delivery. Its frequency has increased in recent years. The authors have set the goal of observing the method of delivery at multifoetal pregnancy over a period of 10 years. In the Obstetrics Clinic there have been 134 bigemine and 3 trigemine deliveries. In 26 pregnant women 18.98% the delivery has been completed by caesarean section. The vaginal deliveries have been 91 (66.43%). In 7 deliveries a forceps has been applied (5.10%). Extraction has been carried out in 12 deliveries (8.&%). On the basis of the accomplished observations the authors have concluded that the vaginal delivery has priority over the abdominal delivery. The latter has to be strictly indicated.

Adult↗